AGRN and BOLL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AGRN	BOLL
Description		agrin	boule homolog, RNA binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Golgi Lumen Plasma Membrane Integral Component Of Membrane Lysosomal Lumen Synapse Collagen-containing Extracellular Matrix Extracellular Exosome	Fibrillar Center Cytoplasm Cytosol Plasma Membrane Flemming Body
	Molecular Function	Dystroglycan Binding Structural Constituent Of Cytoskeleton Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Sialic Acid Binding Chondroitin Sulfate Binding Laminin Binding Heparan Sulfate Proteoglycan Binding	MRNA 3'-UTR Binding Protein Binding Translation Activator Activity
	Biological Process	Cytoskeleton Organization Signal Transduction G Protein-coupled Acetylcholine Receptor Signaling Pathway Neuromuscular Junction Development Animal Organ Morphogenesis Tissue Development Receptor Clustering Positive Regulation Of GTPase Activity Clustering Of Voltage-gated Sodium Channels Positive Regulation Of Synaptic Assembly At Neuromuscular Junction Positive Regulation Of Transcription By RNA Polymerase II Synapse Organization Positive Regulation Of Filopodium Assembly	Spermatogenesis Cell Differentiation Positive Regulation Of Translational Initiation Meiotic Cell Cycle 3'-UTR-mediated MRNA Stabilization
Pathways		A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Integrin cell surface interactions Non-integrin membrane-ECM interactions ECM proteoglycans ECM proteoglycans Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS NCAM1 interactions Defective B3GALT6 causes EDSP2 and SEMDJL1 Retinoid metabolism and transport
Drugs
Diseases
GWAS			Asthma ( 31361310) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Idiopathic dilated cardiomyopathy ( 29495422) Intracranial aneurysm ( 18997786) Morning person ( 30696823) Rheumatoid arthritis ( 32868391) Schizophrenia ( 25056061 29483656) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		11 interacting genes: ATN1 ATXN7 BOLL CACNA1A DAG1 GFI1B HOXA1 MAGED1 NUFIP2 TEPSIN UBC	38 interacting genes: AGPS AGRN ARID5A ATXN2L C1orf94 C4orf45 CBX2 DAZ1 DAZ4 DCANP1 EHHADH FAM168A FOXD4L1 HNRNPLL HYAL3 HYPK INO80B KRTAP19-3 NAF1 NPBWR2 PATZ1 PHF1 POGZ POM121 PRR34 RBFOX2 RBPMS RBPMS2 RHOXF2 SEMA3B SERF2 SNRPC SYCE1L TCEA2 TFG ZBTB32 ZC3H10 ZNF385C
Entrez ID		375790	66037
HPRD ID		10550	07314
Ensembl ID		ENSG00000188157	ENSG00000152430
Uniprot IDs		O00468	Q8N9W6
PDB IDs
Enriched GO Terms of Interacting Partners?
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