ARF1 and AP3S2

Number of citations of the paper that reports this interaction (PubMedID 11926829)
16

Data Source:
BioGRID (pull down)

		ARF1	AP3S2
Description		ADP ribosylation factor 1	adaptor related protein complex 3 subunit sigma 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Late Endosome Peroxisomal Membrane Trans-Golgi Network Cytosol Plasma Membrane Focal Adhesion Postsynaptic Density Sarcomere COPI-coated Vesicle Cell Leading Edge Protein-containing Complex Neuron Projection Perinuclear Region Of Cytoplasm Extracellular Exosome Glutamatergic Synapse	Golgi Apparatus AP-3 Adaptor Complex Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle Axon Cytoplasm
	Molecular Function	Magnesium Ion Binding RNA Binding GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Phospholipase D Activator Activity
	Biological Process	Regulation Of Receptor Internalization Cellular Copper Ion Homeostasis Intracellular Protein Transport Actin Filament Organization Vesicle-mediated Transport Regulation Of Arp2/3 Complex-mediated Actin Nucleation Very-low-density Lipoprotein Particle Assembly Positive Regulation Of Endocytosis Positive Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Protein Secretion Regulation Of Catalytic Activity Golgi To Transport Vesicle Transport Long-term Synaptic Depression Positive Regulation Of Dendritic Spine Development Synaptic Vesicle Budding Dendritic Spine Organization Lysosomal Membrane Organization Cellular Response To Virus Postsynaptic Actin Cytoskeleton Organization Positive Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Late Endosome To Lysosome Transport Positive Regulation Of ER To Golgi Vesicle-mediated Transport Regulation Of Phospholipid Metabolic Process Mitotic Cleavage Furrow Ingression	Intracellular Protein Transport Golgi To Vacuole Transport Anterograde Axonal Transport Vesicle-mediated Transport Anterograde Synaptic Vesicle Transport
Pathways		Synthesis of PIPs at the plasma membrane Synthesis of PIPs at the Golgi membrane Nef Mediated CD4 Down-regulation trans-Golgi Network Vesicle Budding MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		1,3-Propanediol Guanosine-3'-monophosphate-5'-diphosphate Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate Brefeldin A Myristic acid Glycerin
Diseases
GWAS		Adolescent idiopathic scoliosis ( 31417091)	Type 2 diabetes ( 24509480 30054458 21874001 29358691 30297969 23945395 32499647 30718926 28869590) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)
Interacting Genes		47 interacting genes: AGAP1 AGAP2 AP1B1 AP1G1 AP3B1 AP3D1 AP3S2 AP4E1 AP4M1 ARFGAP1 ARFIP1 ARFIP2 ARHGAP21 ASAP1 ASAP2 CHRM3 COPB1 COPE COPG1 CYTH1 CYTH2 DUX4 EEF1G ERBB2 GGA1 GGA2 GGA3 GORAB GOSR2 HTR2A INSR KDELR1 MDM4 NOA1 NPM1 PICK1 PIP5K1A PLD1 PLD2 PLEKHA8 PLIN2 RALA SCYL1 TMED10 TMED2 TMEM106A WBP11	7 interacting genes: AP3B1 AP3D1 AP3S1 ARF1 ARF6 E2F4 SCARB2
Entrez ID		375	10239
HPRD ID		00054	03880
Ensembl ID		ENSG00000143761	ENSG00000157823
Uniprot IDs		A0A024R3Q0 P84077	A0A024RC62 P59780
PDB IDs		1HUR 1RE0 1U81 3O47 4HMY 6CM9 6CRI 6D83 6D84 6DFF 6FAE
Enriched GO Terms of Interacting Partners?
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