KCNA5 and PTPRE

Number of citations of the paper that reports this interaction (PubMedID 15588985)
74

Data Source:
HPRD (in vitro)

		KCNA5	PTPRE
Description		potassium voltage-gated channel subfamily A member 5	protein tyrosine phosphatase receptor type E
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Caveola Voltage-gated Potassium Channel Complex Cell Surface Intercalated Disc Integral Component Of Membrane Z Disc Potassium Channel Complex Membrane Raft Intracellular Canaliculus Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Plasma Membrane Integral Component Of Membrane
	Molecular Function	Signaling Receptor Binding Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Outward Rectifier Potassium Channel Activity Protein Kinase Binding Alpha-actinin Binding Voltage-gated Potassium Channel Activity Involved In Bundle Of His Cell Action Potential Repolarization Voltage-gated Potassium Channel Activity Involved In Atrial Cardiac Muscle Cell Action Potential Repolarization Voltage-gated Potassium Channel Activity Involved In SA Node Cell Action Potential Repolarization Scaffold Protein Binding	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Response To Hypoxia Potassium Ion Transport Notch Signaling Pathway Response To Mechanical Stimulus Response To Organic Substance Regulation Of Vasoconstriction Regulation Of Membrane Potential Response To Hydrogen Peroxide Regulation Of Potassium Ion Transport Regulation Of Insulin Secretion Protein Homooligomerization Negative Regulation Of Cytosolic Calcium Ion Concentration Potassium Ion Homeostasis Response To Hyperoxia Membrane Hyperpolarization Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Potassium Ion Transmembrane Transport Atrial Cardiac Muscle Cell Action Potential Membrane Repolarization During Bundle Of His Cell Action Potential Membrane Repolarization During SA Node Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Potassium Ion Export Across Plasma Membrane Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Myoblast Proliferation	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Insulin Receptor Signaling Pathway
Pathways		Voltage gated Potassium channels
Drugs		Enflurane Promethazine Miconazole Vernakalant Dalfampridine Isavuconazole	Alendronic acid Tiludronic acid
Diseases
GWAS		Longevity ( 30294719)	Response to amphetamines ( 22952603) Select biomarker traits ( 17903293) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		11 interacting genes: ACTN2 DLG1 DLG4 ERBIN KCNA2 PTPRE SNTA1 SRC TMEM107 TNK2 UBE2I	12 interacting genes: FGFR2 FYN GRB2 KCNA5 KCNB1 MAPK1 MAPK3 PTPRD PTPRS SRC TUBB4B YES1
Entrez ID		3741	5791
HPRD ID		08888	02956
Ensembl ID		ENSG00000130037	ENSG00000132334
Uniprot IDs		P22460	A8K2Z9 P23469 Q96P81
PDB IDs			2JJD 6D3F 6D4D 6D4F
Enriched GO Terms of Interacting Partners?
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