KARS1 and MIR9-3

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		KARS1	MIR9-3
Description		lysyl-tRNA synthetase 1	microRNA 9-3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Mitochondrion Mitochondrial Matrix Cytosol Plasma Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex
	Molecular Function	TRNA Binding ATP Adenylyltransferase Activity Lysine-tRNA Ligase Activity Protein Binding ATP Binding Amino Acid Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Basophil Activation Involved In Immune Response Positive Regulation Of Inflammatory Response To Antigenic Stimulus Lysyl-tRNA Aminoacylation TRNA Processing Response To X-ray Diadenosine Tetraphosphate Biosynthetic Process Positive Regulation Of Macrophage Activation Positive Regulation Of Transcription, DNA-templated ERK1 And ERK2 Cascade	Gene Silencing By MiRNA
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation Mitochondrial tRNA aminoacylation
Drugs		L-Lysine
Diseases
GWAS			Schizophrenia ( 28991256 30285260)
Interacting Genes		85 interacting genes: AIMP2 CDC42 DARS2 DYSF EEF1D EEF1G ESR1 FRS3 GAPDH GEMIN4 LINC01554 MAPK1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-2 MIR18B MIR199A1 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR25 MIR29A MIR29B1 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-3 MIR92A1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I OGT PAFAH1B1 PIK3R3 RPSA SLC25A6 SOD1 SPTAN1 SUMO2 VIM	66 interacting genes: ADARB1 APOBEC3B CRTAP DARS1 DDX1 DDX21 DDX3X EIF2AK2 EPRS1 ERAL1 FAM98A FIP1L1 FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LRPPRC MARS1 MATR3 MSI2 NONO P3H1 PDCD11 PRMT1 PTBP1 PUF60 PUM1 QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCB SF3B1 SF3B3 SFPQ STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2B UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346 ZNF385A
Entrez ID		3735	407051
HPRD ID		03249
Ensembl ID		ENSG00000065427	ENSG00000284329
Uniprot IDs		Q15046
PDB IDs		3BJU 4DPG 4YCU 4YCW 6CHD 6ILD 6ILH
Enriched GO Terms of Interacting Partners?
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