GSTK1 and PIP4K2A

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		GSTK1	PIP4K2A
Description		glutathione S-transferase kappa 1	phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Peroxisome Peroxisomal Matrix Cytosol Membrane Extracellular Exosome	Photoreceptor Outer Segment Photoreceptor Inner Segment Nucleoplasm Lysosome Autophagosome Cytosol Plasma Membrane
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Protein Binding	Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidylinositol-5-phosphate 4-kinase Activity Protein Homodimerization Activity
	Biological Process	Glutathione Metabolic Process Epithelial Cell Differentiation Cellular Oxidant Detoxification	Regulation Of Autophagy Phosphorylation Megakaryocyte Development Negative Regulation Of Insulin Receptor Signaling Pathway Autophagosome-lysosome Fusion Vesicle-mediated Cholesterol Transport Negative Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate Biosynthetic Process Positive Regulation Of Autophagosome Assembly
Pathways		Glutathione conjugation Peroxisomal protein import Peroxisomal protein import	Synthesis of PIPs at the plasma membrane PI5P Regulates TP53 Acetylation PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Synthesis of PIPs in the nucleus
Drugs		Glutathione GLUTATHIONE SULFINATE
Diseases
GWAS			Acute lymphoblastic leukemia (B-cell precursor) ( 23996088) Acute lymphoblastic leukemia (childhood) ( 29348612) Acute lymphoblastic leukemia in childhood (B cell precursor) ( 29632299) B-cell acute lymphoblastic leukaemia ( 31767839) Height ( 31562340) Lymphocyte percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Positive urgency ( 30718321) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		7 interacting genes: CCNDBP1 FAM9B GRB2 KRT27 PEX5 PIP4K2A PRPF19	7 interacting genes: BTK GSTK1 MEIS3 ODAD2 RAC1 RPS6KB1 TEC
Entrez ID		373156	5305
HPRD ID		13613	11931
Ensembl ID		ENSG00000197448	ENSG00000150867
Uniprot IDs		Q6FII1 Q9Y2Q3	P48426
PDB IDs		1YZX 3RPN 3RPP	2YBX 6OSP 6UX9
Enriched GO Terms of Interacting Partners?
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