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JUP and RIBC2
Number of citations of the paper that reports this interaction (PubMedID
16189514
)
1103
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
JUP
RIBC2
Description
junction plakoglobin
RIB43A domain with coiled-coils 2
Image
No pdb structure
GO Annotations
Cellular Component
Cornified Envelope
Extracellular Region
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Intermediate Filament
Plasma Membrane
Cell-cell Junction
Adherens Junction
Zonula Adherens
Fascia Adherens
Focal Adhesion
Cytoplasmic Side Of Plasma Membrane
Intercalated Disc
Actin Cytoskeleton
Apicolateral Plasma Membrane
Lateral Plasma Membrane
Catenin Complex
Z Disc
Hemidesmosome
Desmosome
Protein-DNA Complex
Specific Granule Lumen
Extracellular Exosome
Gamma-catenin-TCF7L2 Complex
Ficolin-1-rich Granule Lumen
Nucleus
Molecular Function
Transcription Coactivator Activity
Structural Molecule Activity
Protein Binding
Protein Kinase Binding
Protein Phosphatase Binding
Protein Homodimerization Activity
Protein-containing Complex Binding
Alpha-catenin Binding
Cadherin Binding
Cell Adhesion Molecule Binding
Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication
Cytoskeletal Protein-membrane Anchor Activity
Protein Binding
Biological Process
Positive Regulation Of Cell-matrix Adhesion
Desmosome Assembly
Cell Migration
Regulation Of Cell Population Proliferation
Positive Regulation Of Protein Import Into Nucleus
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Skin Development
Positive Regulation Of Angiogenesis
Positive Regulation Of Transcription By RNA Polymerase II
Detection Of Mechanical Stimulus
Positive Regulation Of DNA-binding Transcription Factor Activity
Endothelial Cell-cell Adhesion
Cellular Response To Indole-3-methanol
Protein Localization To Plasma Membrane
Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication
Regulation Of Heart Rate By Cardiac Conduction
Positive Regulation Of Canonical Wnt Signaling Pathway
Cell-cell Adhesion
Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Pathways
Adherens junctions interactions
VEGFR2 mediated vascular permeability
Neutrophil degranulation
Keratinization
Formation of the cornified envelope
RHOA GTPase cycle
RHOB GTPase cycle
RHOC GTPase cycle
CDC42 GTPase cycle
RHOQ GTPase cycle
RHOH GTPase cycle
RHOJ GTPase cycle
Drugs
Zinc
Zinc acetate
Diseases
GWAS
Heel bone mineral density (
30598549
28869591
)
Major depressive disorder x sex interaction (
34099189
)
Waist circumference (
28552196
)
White matter hyperintensity volume (
33293549
)
White matter hyperintensity volume (adjusted for hypertension) (
33293549
)
White matter hyperintensity volume x hypertension interaction (2df) (
33293549
)
Interacting Genes
53 interacting genes:
APC
ARHGDIA
AXIN1
BIRC2
BRCA1
BTRC
CDH1
CDH10
CDH15
CDH2
CDH5
CTNNA1
CTNNA3
CTNNBIP1
CTNND1
DDX6
DSC1
DSC2
DSC3
DSG1
DSG2
DSG3
DSP
EGFR
ERBB2
ERBB3
FER
FHL2
FYN
HSP90AA1
MUC1
NFATC4
NFKBIE
NTAQ1
PECAM1
PKD1
PKP2
PKP3
PRR35
PSEN1
PTEN
PTPN14
PTPRF
PTPRJ
PTPRK
RIBC2
RSPH14
SRC
TBP
TCF4
TCF7L2
YJU2B
ZFYVE9
23 interacting genes:
AP2B1
BEGAIN
CCDC85B
EFEMP2
GFAP
GTPBP3
HOOK2
JUP
KRT15
MTUS2
NINL
NRBP1
PJA1
RAD54B
RPL18A
SARAF
TEX11
TRAF2
TREX1
TRIM23
TRIM37
USHBP1
VIM
Entrez ID
3728
26150
HPRD ID
01414
11493
Ensembl ID
ENSG00000173801
ENSG00000128408
Uniprot IDs
A0A0S2Z487
P14923
Q9H4K1
PDB IDs
3IFQ
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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