Description |
Jun proto-oncogene, AP-1 transcription factor subunit |
mitogen-activated protein kinase 10 |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Minocycline
- Pyrazolanthrone
- Cyclohexyl-{4-[5-(3,4-Dichlorophenyl)-2-Piperidin-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine
- Cyclopropyl-{4-[5-(3,4-Dichlorophenyl)-2-[(1-Methyl)-Piperidin]-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine
- 9-(4-Hydroxyphenyl)-2,7-Phenanthroline
- Phosphoaminophosphonic Acid-Adenylate Ester
- N-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamide
- N-BENZYL-4-[4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL]-1H-PYRROLE-2-CARBOXAMIDE
- N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamide
- 4-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-N-ethylpiperidine-1-carboxamide
- (3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-[(E)-2-phenylethenyl]-1H-indole-2,3-dione 3-oxime
- (3E)-5-fluoro-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-1H-indole-2,3-dione 3-oxime
- (3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-phenyl-1H-indole-2,3-dione 3-oxime
- 5-bromo-N-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamide
- N-cyclohexyl-4-imidazo[1,2-a]pyridin-3-yl-N-methylpyrimidin-2-amine
- N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE
- 2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-N-methylacetamide
- 1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline
- Fostamatinib
- Halicin
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Diseases |
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GWAS |
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- Cleft lip with or without cleft palate x maternal periconceptional smoking interaction (parent of origin effect) ( 31372216)
- Cobalt levels ( 26025379)
- Diisocyanate-induced asthma ( 25918132)
- Gait speed in old age ( 28077804)
- Liver enzyme levels (alanine transaminase) ( 33972514 22001757)
- Multiple sclerosis ( 31604244)
- Peripheral artery disease ( 25009551)
- Response to cytidine analogues (gemcitabine) ( 24483146)
- Triglyceride levels ( 32203549 32154731)
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Interacting Genes |
189 interacting genes:
ABL1
AKAP5
APLP2
APP
AR
ARRB1
ATF1
ATF2
ATF3
ATF4
BATF
BATF2
BBS7
BCL3
BCL6
BLM
BRCA1
CASP9
CCND1
CEBPE
CEBPG
CLINT1
COP1
COPS5
CREB3
CREB5
CREBBP
CSNK2A1
DAB1
DACH1
DDIT3
DDX21
DHX9
DNMT3L
EDF1
EGR1
ELF3
ELOF1
EN1
EP300
EPAS1
ERG
ESR1
ETS1
ETS2
ETV1
ETV4
EWSR1
FBXW7
FOS
FOSB
FOSL1
FOSL2
GART
GATA2
GOPC
GPR18
GSK3B
GTF2B
GTF2E2
GTF2F1
GTF2F2
HCFC1
HDAC3
HDAC9
HDGF
HHEX
HIF1A
HMGA1
HNRNPM
HOXA9
HOXC8
HSP90AA1
HSPA8
IKBKB
IRAK1
ISCU
ITCH
ITPK1
JDP2
KLF5
KMT2C
KPNA2
M6PR
MACF1
MAF
MAFB
MAP2K4
MAP2K7
MAPK1
MAPK10
MAPK11
MAPK14
MAPK3
MAPK8
MAPK9
MAPKAPK5
MAPRE3
MBD3
MDM2
MOK
MTA1
MYBBP1A
MYOD1
NACA
NAT14
NCOA1
NCOA2
NCOA3
NCOA6
NCOR2
NEDD4
NELFB
NFE2L1
NFE2L2
NFYA
NFYC
NR3C1
NR5A1
NRIP1
NTRK3
PACS1
PHOX2A
PIAS1
PIAS2
PIN1
PML
POU1F1
PPARG
PPP3CB
PPP4C
PRKD1
PRKDC
PRRC2A
RB1
RBM39
RELA
RNF187
ROR1
RPL18A
RPS6KA2
RUNX1
RUNX2
SKI
SMAD2
SMAD3
SMAD4
SMARCD1
SMARCD3
SNAPC5
SNIP1
SNRK
SOX10
SOX8
SP1
SPI1
SPIB
STAT1
STAT3
STAT4
STRN4
SUMO1
SUMO2
SUMO3
SUMO4
TACSTD2
TAF1
TAF4
TBP
TCF20
TCF4
TDG
TGIF1
TOP1
TOP2A
TP53
TPM1
TPM2
TRAF2
TRIP4
TSC22D3
TSG101
UBB
UBC
UBE2I
USP6
VAV1
VDR
ZBTB7C
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40 interacting genes:
APP
ARRB1
ARRB2
ATF2
BCL2L11
CDK5
CDKN1B
CDKN2A
CDKN2C
CEP290
CREBBP
DUSP10
DUSP16
DUSP9
ELK1
FBXO7
GTF3C1
HAX1
HDAC9
HNRNPK
HRAS
JUN
KIF26A
KIF5A
LDHA
MAP2K4
MAPK8IP2
MAPK8IP3
MAPKBP1
MAPT
MCL1
PKMYT1
PLIN2
RELA
SH3BP5
STMN2
TNIP1
TP53
UBE3A
UNC119
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Entrez ID |
3725 |
5602 |
HPRD ID |
01302 |
04207 |
Ensembl ID |
ENSG00000177606
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ENSG00000109339
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Uniprot IDs |
P05412
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A0A1P0B7D2
A0A286YEQ7
A0A286YES0
A0A286YF02
A0A286YF97
A0A286YFD7
A0A286YFN2
D6RCB1
D6RJF9
F8W9R5
I6L9F3
P53779
Q499Y8
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PDB IDs |
1A02
1FOS
1JNM
1JUN
1S9K
1T2K
5FV8
5T01
6Y3V
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1JNK
1PMN
1PMU
1PMV
2B1P
2EXC
2O0U
2O2U
2OK1
2P33
2R9S
2WAJ
2ZDT
2ZDU
3CGF
3CGO
3DA6
3FI2
3FI3
3FV8
3G90
3G9L
3G9N
3KVX
3OXI
3OY1
3PTG
3RTP
3TTI
3TTJ
3V6R
3V6S
4H36
4H39
4H3B
4KKE
4KKG
4KKH
4U79
4W4V
4W4W
4W4X
4W4Y
4WHZ
4X21
4Y46
4Y5H
4Z9L
6EKD
6EMH
6EQ9
7KSI
7KSJ
7KSK
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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