TNFRSF9 and AP1S1

		TNFRSF9	AP1S1
Description		TNF receptor superfamily member 9	adaptor related protein complex 1 subunit sigma 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin-coated Pit Membrane AP-1 Adaptor Complex Cytoplasmic Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Cytokine Binding Signaling Receptor Activity	Clathrin Adaptor Activity
	Biological Process	Apoptotic Process Negative Regulation Of Cell Population Proliferation Regulation Of Cell Population Proliferation	Intracellular Protein Transport Receptor-mediated Endocytosis Response To Virus Vesicle-mediated Transport
Pathways		TNFs bind their physiological receptors	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs		Urelumab
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Celiac disease ( 20190752) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Psoriasis ( 25903422 23143594) Rheumatoid arthritis ( 30423114 24390342) Ulcerative colitis ( 28067908 21297633) Waist-hip ratio ( 28552196)	Adult body size ( 32376654) Serum metabolite concentrations in chronic kidney disease ( 33838163)
Interacting Genes		13 interacting genes: AP1S1 CRY2 IDH3B IMP3 LRR1 MUTYH SERP1 SLC7A10 TNFRSF4 TNFSF9 TRAF1 TRAF2 TRAF3	7 interacting genes: AP1G1 AP1G2 AP1M2 AP2A2 PICK1 RHOU TNFRSF9
Entrez ID		3604	1174
HPRD ID		03767	04635
Ensembl ID		ENSG00000049249	ENSG00000106367
Uniprot IDs		Q07011	A0A024QYT6 P61966
PDB IDs		6A3V 6A3W 6BWV 6CPR 6CU0 6MGP 6MHR 6MI2 6Y8K	4P6Z
Enriched GO Terms of Interacting Partners?
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