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AQP1 and KRT40
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
484
Data Source:
BioGRID
(two hybrid)
AQP1
KRT40
Description
aquaporin 1 (Colton blood group)
keratin 40
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Symbiont-containing Vacuole Membrane
Brush Border Membrane
Nuclear Membrane
Sarcolemma
Apical Part Of Cell
Extracellular Exosome
Cytosol
Intermediate Filament
Molecular Function
Intracellular CGMP-activated Cation Channel Activity
Potassium Channel Activity
Water Transmembrane Transporter Activity
Protein Binding
Ammonium Transmembrane Transporter Activity
Potassium Ion Transmembrane Transporter Activity
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Transmembrane Transporter Activity
Nitric Oxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transporter Activity
Identical Protein Binding
Structural Molecule Activity
Protein Binding
Biological Process
Renal Water Homeostasis
Renal Water Transport
Potassium Ion Transport
Water Transport
Cell Volume Homeostasis
Hyperosmotic Response
Cellular Water Homeostasis
Carbon Dioxide Transport
Ammonium Transport
Glycerol Transport
Cellular Homeostasis
CGMP-mediated Signaling
Lateral Ventricle Development
Pancreatic Juice Secretion
Nitric Oxide Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Cerebrospinal Fluid Secretion
Cellular Response To UV
Transepithelial Water Transport
Carbon Dioxide Transmembrane Transport
Odontogenesis
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of Saliva Secretion
Positive Regulation Of Fibroblast Proliferation
Defense Response To Gram-negative Bacterium
Multicellular Organismal Water Homeostasis
Cellular Response To Hydrogen Peroxide
Cellular Response To Inorganic Substance
Cellular Response To Mechanical Stimulus
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Cellular Response To Retinoic Acid
Cellular Response To CAMP
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Hyperosmotic Response
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Potassium Ion Transmembrane Transport
Ammonium Transmembrane Transport
Pathways
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Keratinization
Formation of the cornified envelope
Drugs
Acetazolamide
B-nonylglucoside
Mersalyl
Diseases
GWAS
Fractures (
30598549
)
Heel bone mineral density (
30598549
28869591
)
hemolysis of donated blood (osmotic) (
34014839
)
Huntington's disease progression (
28642124
)
Kidney stones (
31729369
)
Nephrolithiasis (
22396660
)
Systolic blood pressure (
30224653
)
Total body bone mineral density (
29304378
)
Triglyceride levels (
34074324
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Gut microbiota (bacterial taxa, rank normal transformation method) (
32572223
)
Interacting Genes
134 interacting genes:
ADAMTSL4
AMOT
AQP6
BCL2L13
BEGAIN
BHLHB9
BLZF1
BMF
CCDC136
CCDC57
CCDC85B
CCNDBP1
CD79A
CDR2
CEP44
CLDN5
COMP
CPLX4
CREB3
CRTAC1
CSRNP1
CYSRT1
EFEMP2
EPHB2
ESM1
EVI2B
FAM161A
FAM209A
FNDC9
FOS
FSD2
GET1
GJB5
GLI1
GOLGA2
GPR37L1
GPX8
IFT20
IGFBP6
IHO1
IKZF2
IKZF3
IL21R
KCNK5
KCTD17
KCTD9
KHDRBS3
KIAA1958
KLHL26
KRT31
KRT33B
KRT37
KRT40
KRTAP1-1
KRTAP1-5
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP12-4
KRTAP3-2
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP6-2
KRTAP9-2
KRTAP9-8
LCE1A
LDLRAD1
LDOC1
LIME1
LMNA
LPXN
LRRC59
MDFI
MGST3
MID2
MIF4GD
MKRN3
MRM1
MTUS2
MUC1
MYF5
NBPF19
NBPF22P
NBPF6
NOTCH2NLA
NUTM1
PGPEP1
PICK1
PLA2G10
PLSCR2
PPARA
PRDM14
PRDM6
RBAK
REL
RGS17
RGS20
RIMBP3
RNF122
SAR1A
SIAH1
SIVA1
SLC15A2
SLC39A2
SPDYA
SPRED1
SPRED2
SPRY2
SPRY3
SPRYD7
SSMEM1
TCF4
TMEM237
TMEM38B
TMEM45B
TMEM80
TMPRSS2
TNK2
TNS2
TRAF1
TRAF2
TRIM23
TRIM37
TRIM41
TRIM42
TRIM7
TRIP6
TSC1
ZBTB39
ZIM2
ZNF16
ZNF398
ZNF792
381 interacting genes:
ACSF3
ADAMTS1
ADAMTSL3
AEN
AGXT
AKAP17A
ALDH3B1
ANKRD36BP1
AP1M1
AQP1
AQP5
ARID5A
ARMC7
ARSI
ASMTL
ATPAF2
AVPI1
AXIN1
BAHD1
BARD1
BCAS2
BEX2
BMS1P1
BRME1
BYSL
C10orf62
C11orf87
C19orf73
C1orf109
C1orf216
C22orf46
C2CD6
C2orf68
C4orf45
C5orf60
C6orf226
C8orf48
CA6
CARD9
CATIP
CBX8
CCDC112
CCDC116
CCDC120
CCDC146
CCDC185
CCDC198
CCDC26
CCDC93
CCER1
CCHCR1
CCNG1
CD33
CDC20B
CDK18
CDK5R1
CELA2B
CEP57
CEP57L1
CFAP206
CHCHD2
CHCHD3
CHIC2
CLEC18A
CNNM3
CNTF
COL8A1
COMT
COX5A
CREB5
CRY2
CTSZ
CWF19L2
CYCS
CYTH4
DAAM2
DCDC2B
DCX
DDX6
DHX57
DLGAP2
DMRT3
DOCK2
DOCK8
DTNB
EIF4E2
ELOA
ENKD1
EXOC3-AS1
FADS2
FAM107A
FAM124B
FAM214A
FAM27E3
FAM71C
FAM74A4
FAM90A1
FARS2
FASLG
FBF1
FBXL18
FBXO34
FBXW5
FEZF1
FKBP1B
FNDC11
FOXB1
FRG1
GAD1
GADD45GIP1
GATA2
GATAD2A
GEM
GFOD1
GGN
GLIDR
GNAI2
GNE
GNG5
GOLGA6L2
GPATCH2L
GTF3C5
GUCD1
HAPLN2
HAUS1
HBA2
HBZ
HCK
HDAC4
HGS
HNRNPLL
HOXA1
HOXB9
HOXC8
HSD3B7
HSF4
HSPA12B
HSPD1
ING5
INO80B
INPP5D
IQUB
ISCU
ITGB4
ITGB5
JOSD1
KANK2
KAT5
KCTD9
KDM1A
KIFC3
KLHL38
KPNA2
KRT2
KRT20
KRT4
KRT5
KRT6A
KRT6B
KRT6C
KRT71
KRT72
KRT75
KRT76
KRT8
KRT81
KRT82
KRT83
KRT85
KRT86
LAGE3
LCE3E
LENG1
LHX4
LIMS2
LIN37
LINC00636
LINC01588
LMF2
LMO1
LMO2
LMO4
LRCH4
MAB21L2
MAGOHB
MAPKBP1
MARK4
MED8
METTL17
MFAP1
MID2
MOB3C
MOBP
MOS
MRPL11
MRRF
MSRB3
MTA1
MXI1
MYPOP
NAB2
NAPRT
NDEL1
NEK6
NFKBID
NINJ1
NOL4L-DT
NPBWR2
NPPB
NR1D2
NXF1
ODAD4
OIP5
OPCML
OTUB2
PDLIM5
PGLS
PHF1
PHF21A
PHLDA1
PIGS
PIMREG
PIN1
PKD2
POLDIP3
POLL
POM121L8P
POP5
PPP1R18
PRAM1
PRKAA1
PRKAB2
PRPF18
PRPF31
PSMA1
PSMB1
PSMC5
PTGER3
PTPMT1
PXMP2
QPRT
RAB3IL1
RAB3IP
RAC1
RASSF5
RBM41
RCOR3
RECK
RGS8
RNF213
RNF6
RPL11
RSPH14
RTP5
RWDD2B
RXRB
SCAND1
SCOC
SEMA4C
SETD5
SH2D4A
SHC3
SHFL
SIRPA
SLC23A1
SLC25A10
SLIRP
SLU7
SMARCE1
SMCO4
SNAI1
SNHG11
SNRPB
SNW1
SPATA24
SPATC1L
SPEF1
SPG7
SRSF2
SSX2
SSX2IP
SUOX
SYT6
TACO1
TAPBPL
TBC1D16
TBC1D21
TBC1D22B
TCEA2
TCEANC
TCHP
TEAD4
THAP7
TIE1
TLE5
TMEM231
TMEM241
TMSB4X
TNIP3
TNNT1
TRAF4
TRIM42
TROAP
TRPV6
TSC22D4
TSGA10IP
TSHZ3
TTC23
TTC9C
TTLL10
TXLNA
TXN2
TXNDC5
TYK2
TYRO3
UACA
UBASH3A
UCMA
USHBP1
USP2
USP21
UTP14C
UTP23
UXT
VEZF1
WDR25
WT1
WT1-AS
ZBTB16
ZBTB24
ZBTB38
ZBTB42
ZC2HC1C
ZFHX3
ZFP1
ZFP2
ZFP69B
ZFYVE21
ZFYVE26
ZGPAT
ZMAT2
ZNF101
ZNF124
ZNF138
ZNF165
ZNF17
ZNF20
ZNF202
ZNF230
ZNF250
ZNF26
ZNF266
ZNF286A
ZNF317
ZNF319
ZNF329
ZNF337
ZNF408
ZNF410
ZNF417
ZNF438
ZNF439
ZNF446
ZNF488
ZNF490
ZNF564
ZNF569
ZNF575
ZNF580
ZNF581
ZNF587
ZNF625
ZNF655
ZNF688
ZNF697
ZNF702P
ZNF76
ZNF792
ZNF844
ZNRF2P1
ZSCAN21
Entrez ID
358
125115
HPRD ID
00140
08304
Ensembl ID
ENSG00000240583
ENSG00000204889
Uniprot IDs
A0A024RA31
P29972
Q6A162
PDB IDs
1FQY
1H6I
1IH5
4CSK
6POJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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