LCE3E and PLSCR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LCE3E	PLSCR2
Description		late cornified envelope 3E	phospholipid scramblase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Endoplasmic Reticulum Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Phospholipid Scramblase Activity
	Biological Process	Keratinization	Plasma Membrane Phospholipid Scrambling
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 26482879) Common traits (Other) ( 20585627) Inflammatory skin disease ( 25574825) Plantar warts ( 28928442) Psoriasis ( 25854761)	Hip circumference ( 28552196)
Interacting Genes		51 interacting genes: ADAMTSL4 ALPP CYSRT1 EFEMP2 GRN GSC2 HOXA1 KPRP KRT31 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 MACO1 MDFI NBPF19 NOTCH2NLA NXF1 PLSCR2 RGS17 RGS20 SPRY2 SPRY3 TRIM42 VWC2	15 interacting genes: AQP1 BSND COQ9 EP300 FAM221B GNG13 HOXA1 LCE1A LCE3A LCE3E LCE5A LYPD1 OTX1 POU4F2 PSMD8
Entrez ID		353145	57047
HPRD ID		13975	09621
Ensembl ID		ENSG00000185966	ENSG00000163746
Uniprot IDs		Q5T5B0	Q9NRY7
PDB IDs
Enriched GO Terms of Interacting Partners?
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