LCE3A and PLSCR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LCE3A	PLSCR2
Description		late cornified envelope 3A	phospholipid scramblase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Endoplasmic Reticulum Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Phospholipid Scramblase Activity
	Biological Process	Keratinization Killing Of Cells Of Other Organism Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium	Plasma Membrane Phospholipid Scrambling
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 23727859) Inflammatory skin disease ( 25574825) Psoriasis ( 19169255) Psoriasis vulgaris ( 26626624)	Hip circumference ( 28552196)
Interacting Genes		61 interacting genes: ADAMTSL4 ALPP CHIC2 CYSRT1 EFEMP1 EFEMP2 FBLN1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1C LCE2A LCE2B LCE2C LCE3B MACO1 MDFI NBPF19 NOTCH2NLA OIT3 PLSCR2 RGS17 RGS20 SMCP SPRY1 SPRY3 TGFB1 TGM1 TRIM42 TSPAN4 VWC2 VWC2L	15 interacting genes: AQP1 BSND COQ9 EP300 FAM221B GNG13 HOXA1 LCE1A LCE3A LCE3E LCE5A LYPD1 OTX1 POU4F2 PSMD8
Entrez ID		353142	57047
HPRD ID		13973	09621
Ensembl ID		ENSG00000185962	ENSG00000163746
Uniprot IDs		Q5TA76	Q9NRY7
PDB IDs
Enriched GO Terms of Interacting Partners?
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