Description |
insulin like growth factor 1 receptor |
N-acetyltransferase 2 |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Apolipoprotein A1 levels ( 32203549)
- Apolipoprotein B levels ( 32203549)
- Bladder cancer ( 24163127 20972438)
- Blood metabolite levels ( 24816252)
- Blood metabolite ratios ( 24816252)
- Cholesterol, total ( 24097068 20686565)
- Coronary artery disease ( 29212778 33020668)
- Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
- Insulin resistance/response ( 25798622)
- Iron status biomarkers (total iron binding capacity) ( 33536631)
- Iron status biomarkers (transferrin levels) ( 25352340)
- LDL cholesterol levels ( 32203549)
- LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Liver enzyme levels (alkaline phosphatase) ( 33972514)
- Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
- Liver injury in anti-tuberculosis drug treatment ( 31109976)
- Medication use (calcium channel blockers) ( 31015401)
- Medication use (HMG CoA reductase inhibitors) ( 31015401)
- Metabolic syndrome ( 31589552)
- Metabolic traits ( 21886157)
- Metabolite levels ( 23823483)
- Myocardial infarction ( 33532862)
- Night sleep phenotypes ( 27126917)
- Paclitaxel-induced neuropathy ( 23776197)
- Serum metabolite levels ( 33031748)
- Total cholesterol levels ( 28334899 33339817)
- Triglyceride levels ( 32203549 28334899 29403010 33339817 30698716)
- Triglyceride levels in current drinkers ( 30698716)
- Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Triglyceride levels x long total sleep time interaction (2df test) ( 31719535)
- Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
- Triglycerides ( 24097068 20686565)
- Urinary metabolite levels in chronic kidney disease ( 31959995)
- Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
- Urinary metabolites ( 26352407 21572414)
- Urinary metabolites (H-NMR features) ( 24586186)
- Youthful appearance (self-reported) ( 32339537)
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Interacting Genes |
95 interacting genes:
AMY2A
APP
ARHGEF12
BAP1
CAV1
CBL
CDK4
CDKN2B
CRK
CRKL
CSK
CYP17A1
DOK4
DOK5
DUSP10
DUSP14
DUSP15
DUSP18
DUSP19
DUSP21
DUSP26
DUSP29
EEA1
EHD1
ERBB2
ESR1
FFAR2
FGFR4
GIPC1
GNAI1
GNAI2
GRB10
GRB14
GRM1
HOXC6
IGF1
IGF2
IGFBP3
IL13RA2
ILKAP
INS
INSR
IRS1
IRS2
IRS4
ITGB1
JAK1
JAK2
KCNIP3
KDELR2
KL
KLK5
KRT27
LYPD3
MAP3K5
MDM2
MTA3
NAT2
NEDD4
NF2
PCSK6
PIK3R1
PIK3R2
PIK3R3
PPM1A
PRKCD
PRKD1
PTPN1
PTPN11
PTPN12
PTPN6
PTPN7
PTPRR
RACK1
RASA1
RELA
RPL11
SH2B1
SHC1
SIRPA
SOCS1
SOCS2
SOCS3
SRC
STAT3
STYX
THRSP
TTYH2
UBC
VAV3
VPS45
YWHAB
YWHAE
YWHAG
YWHAZ
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18 interacting genes:
APC
APP
AURKA
BAG4
CDKN2A
CDKN2C
CLU
ERBB2
FZR1
HMMR
IGF1R
MBD4
NAA10
NBN
PALB2
PPM1D
STK11
WT1
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Entrez ID |
3480 |
10 |
HPRD ID |
00932 |
02000 |
Ensembl ID |
ENSG00000140443
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ENSG00000156006
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Uniprot IDs |
C9J5X1
P08069
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A4Z6T7
P11245
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PDB IDs |
1IGR
1JQH
1K3A
1M7N
1P4O
2OJ9
2ZM3
3D94
3F5P
3I81
3LVP
3LW0
3NW5
3NW6
3NW7
3O23
3QQU
4D2R
4XSS
5FXQ
5FXR
5FXS
5HZN
5U8Q
5U8R
6JK8
6VWG
6VWH
6VWI
6VWJ
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2PFR
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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