SLC35B2 and ASGR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC35B2	ASGR2
Description		solute carrier family 35 member B2	asialoglycoprotein receptor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Integral Component Of Membrane Integral Component Of Golgi Membrane Integral Component Of Endoplasmic Reticulum Membrane	Plasma Membrane Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Transmembrane Transporter Activity 3'-phosphoadenosine 5'-phosphosulfate Transmembrane Transporter Activity	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding
	Biological Process	Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling 3'-phosphoadenosine 5'-phosphosulfate Transport 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process 3'-phospho-5'-adenylyl Sulfate Transmembrane Transport	Endocytosis Cell Surface Receptor Signaling Pathway Glycoprotein Metabolic Process Bone Mineralization Regulation Of Protein Stability Lipid Homeostasis
Pathways		Transport and synthesis of PAPS Transport of nucleotide sugars	Asparagine N-linked glycosylation
Drugs			Antihemophilic factor, human recombinant Lonoctocog alfa Moroctocog alfa
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Blood protein levels ( 29875488) Congenital heart disease (maternal effect) ( 28468790) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Liver enzyme levels (alkaline phosphatase) ( 33972514) Total cholesterol levels ( 30275531)
Interacting Genes		14 interacting genes: AQP6 ASGR2 CD69 CLDN15 CREB3L1 CYB5R3 ERGIC3 GOLM1 LMNA RNF170 SHISAL1 TEX29 TMEM237 TMEM248	51 interacting genes: ADAM33 ADIPOQ AIG1 ASGR1 ATP6V0C BET1 CD53 CERS2 CLEC17A CLEC7A CTNNB1 EMP1 F8 FA2H FATE1 GLP1R GLUD1 HES1 HMOX2 HNF1B IL1RL1 LAT LNPEP MCEMP1 MMD2 MROH5 MS4A13 NRG1 ORMDL1 PLN PLP2 PMP22 RPRM SEC22A SLC35A1 SLC35B2 SMIM3 STX8 TFRC TMEM140 TMEM60 TMEM86B TMPPE TRAM1L1 TSPO2 UBIAD1 UPK2 VAMP5 VKORC1 VTI1B YIPF1
Entrez ID		347734	433
HPRD ID		11576	00152
Ensembl ID		ENSG00000157593	ENSG00000161944
Uniprot IDs		Q8TB61	P07307 Q7Z4G9
PDB IDs
Enriched GO Terms of Interacting Partners?
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