SP110 and NAP1L2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		SP110	NAP1L2
Description		SP110 nuclear body protein	nucleosome assembly protein 1 like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Chromatin Nucleus
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Metal Ion Binding	Chromatin Binding Protein Binding Histone Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Nucleosome Assembly Positive Regulation Of Neuron Differentiation Positive Regulation Of Histone H3-K14 Acetylation Regulation Of Stem Cell Division Positive Regulation Of Histone H3-K9 Acetylation
Pathways
Drugs
Diseases
GWAS		B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025) Chronic lymphocytic leukemia ( 18758461 28165464 24292274) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Obesity-related traits ( 23251661) Subcutaneous adipose tissue ( 26480920)	Bipolar disorder ( 31043756)
Interacting Genes		12 interacting genes: AGAP1 ANXA7 CDKN1A NAP1L2 NDUFV2 OSGEP RUNX3 SMN1 TK1 TSC22D1 TTR ZSCAN9	14 interacting genes: CCDC146 CCDC185 DMAP1 FAM81A KLHL2 MED30 NAP1L1 NAP1L5 POFUT1 PPP1R13B PPP3R1 SCNM1 SH3BP5 SP110
Entrez ID		3431	4674
HPRD ID		06832	02066
Ensembl ID		ENSG00000135899	ENSG00000186462
Uniprot IDs		Q9HB58	Q9ULW6
PDB IDs
Enriched GO Terms of Interacting Partners?
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