IDH3B and RAB35

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		IDH3B	RAB35
Description		isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta	RAB35, member RAS oncogene family
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GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix	Cytosol Plasma Membrane Clathrin-coated Pit Endosome Membrane Clathrin-coated Endocytic Vesicle Membrane Cell Projection Membrane Melanosome Intercellular Bridge Clathrin-coated Endocytic Vesicle Recycling Endosome Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Magnesium Ion Binding Isocitrate Dehydrogenase (NAD+) Activity Electron Transfer Activity NAD Binding	GTPase Activity Protein Binding GTP Binding Phosphatidylinositol-4,5-bisphosphate Binding GDP Binding
	Biological Process	Tricarboxylic Acid Cycle Isocitrate Metabolic Process 2-oxoglutarate Metabolic Process NADH Metabolic Process Electron Transport Chain	Mitotic Cytokinesis Protein Localization Protein Transport Endosomal Transport Antigen Processing And Presentation Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Protein Localization To Endosome Plasma Membrane To Endosome Transport Cellular Response To Nerve Growth Factor Stimulus
Pathways		Citric acid cycle (TCA cycle)	TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs		NADH
Diseases
GWAS			Heel bone mineral density ( 30598549)
Interacting Genes		7 interacting genes: ATXN2 IDH3A IDH3G MAPK6 PRMT1 RAB35 TNFRSF9	10 interacting genes: APP CALCOCO2 CBR3 GNPAT IDH3B MPHOSPH9 PTPRS TBPL1 TRIM54 WDCP
Entrez ID		3420	11021
HPRD ID		05163	05010
Ensembl ID		ENSG00000101365	ENSG00000111737
Uniprot IDs		A0A087WZN1 A0A087X2E5 O43837	Q15286
PDB IDs		6KDE 6KDF 6KDY 6KE3 7CE3	3TW8 6EKK 6IF2 6IF3
Enriched GO Terms of Interacting Partners?
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