ID3 and GUCD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ID3	GUCD1
Description		inhibitor of DNA binding 3, HLH protein	guanylyl cyclase domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Protein Domain Specific Binding Protein Dimerization Activity Transcription Regulator Activity Transcription Regulator Inhibitor Activity Leptomycin B Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Metanephros Development Regulation Of DNA Replication Multicellular Organism Development Central Nervous System Development Heart Development Muscle Organ Development Response To Wounding Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Differentiation Neuron Differentiation Epithelial Cell Differentiation Notochord Development Circadian Regulation Of Gene Expression Odontogenesis Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Myoblast Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle Cellular Response To Leptomycin B
Pathways		NGF-stimulated transcription
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
Interacting Genes		50 interacting genes: ADD1 ANKS1A ATF3 BOLA2 BOLA2B C22orf39 CBFA2T2 CDK2 CEP350 CNOT3 CREB5 CSK E2F4 ELK1 ELK4 FAM74A1 FHL2 FRS3 GATA4 GNB2 GTF2A1L GUCD1 HES1 HOXA1 ID4 IFI16 IKBKG KAT5 KRTAP26-1 LMO4 MLX MSGN1 MYF5 MYF6 MYOD1 MYOG PAX5 PRDM14 PUF60 RND1 RUNX1T1 SAP30 SDCBP SREBF1 TCF12 TCF3 TCF4 ZNF3 ZNF408 ZNF626	77 interacting genes: ADAM12 ADAMTSL4 APP ATP23 BEGAIN CCDC153 CPSF7 CRX CTAG1A CTAG1B CTH CYSRT1 FCHO1 FHL3 FUCA2 HESX1 HOXA1 HSPB7 ID3 ISCA2 KATNBL1 KPRP KRT40 KRTAP1-1 KRTAP1-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP13-3 KRTAP19-5 KRTAP19-6 KRTAP3-2 KRTAP3-3 KRTAP4-2 KRTAP5-6 KRTAP5-7 KRTAP9-2 KRTAP9-8 LASP1 LCE1C LCE2A LCE2B LCE2D LHX3 LNX1 MAP2K5 MEOX2 MORN3 MORN4 NDUFAF6 NGLY1 PCBD2 PCSK5 PFDN5 PSMA1 PTH1R RSPO4 RUNX3 SLC25A48 SMCP SPRY1 SYNGAP1 TCF4 TEPSIN TFAP2D TOLLIP TRIM42 TSPAN4 TXN2 VASN YPEL3 ZBTB42 ZCCHC13 ZNF250 ZNF655 ZNF705D ZNF835
Entrez ID		3399	83606
HPRD ID		02608	12796
Ensembl ID		ENSG00000117318	ENSG00000138867
Uniprot IDs		Q02535	A0A024R1B8 A0A087WVD9 B4DL90 E7EX77 E9PGZ7 Q7Z629 Q96NT3
PDB IDs		2LFH
Enriched GO Terms of Interacting Partners?
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