KRTAP6-3 and LGALS9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KRTAP6-3	LGALS9
Description		keratin associated protein 6-3	galectin 9
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Extracellular Space Nucleus Cytoplasm Cytosol Collagen-containing Extracellular Matrix
	Molecular Function		Galactose Binding Galactoside Binding Enzyme Binding Carbohydrate Binding Disaccharide Binding
	Biological Process	Keratinization	Natural Killer Cell Tolerance Induction Chemotaxis Inflammatory Response Female Pregnancy Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Response To Lipopolysaccharide Regulation Of Interleukin-4 Production Regulation Of Interleukin-5 Production Negative Regulation Of Chemokine Production Negative Regulation Of Interferon-gamma Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-12 Production Positive Regulation Of Interleukin-13 Production Positive Regulation Of Interleukin-4 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Interleukin-8 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Involved In Immune Response Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 4 Signaling Pathway P38MAPK Cascade Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Mast Cell Degranulation Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Activated T Cell Proliferation Positive Regulation Of Viral Entry Into Host Cell Positive Regulation Of NF-kappaB Transcription Factor Activity Maternal Process Involved In Female Pregnancy Positive Regulation Of Activated T Cell Autonomous Cell Death ERK1 And ERK2 Cascade Positive Regulation Of ERK1 And ERK2 Cascade Response To Interleukin-1 Cellular Response To Interferon-gamma Positive Regulation Of Transforming Growth Factor Beta Production Positive Regulation Of Monocyte Chemotactic Protein-1 Production Mature Conventional Dendritic Cell Differentiation Cellular Response To Virus Regulation Of P38MAPK Cascade Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Dendritic Cell Chemotaxis Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of Dendritic Cell Apoptotic Process Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Positive Regulation Of Dendritic Cell Differentiation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway
Pathways			Interleukin-2 family signaling
Drugs			(R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Crohn's disease ( 23128233) Irritable mood ( 29500382)
Interacting Genes		159 interacting genes: ADAMTSL4 AGXT ARID5A ARMC7 ATPAF2 AUTS2 BAG4 BEX2 BSCL2 C11orf87 CAMK2A CAMK2B CAMK2G CARHSP1 CCDC120 CCDC24 CCER1 CELF5 CHRD CLCNKA CNNM3 COL8A1 CREB5 CRY2 CTSZ CYSRT1 DALRD3 DHRS1 DMRT3 FADS6 FAM214B FAM83A FBXW5 FCHO1 FOXD2 FOXD4L1 GATA2 GATA3 GLYCTK GNE GPS2 HAPLN2 HHEX HOXA1 HOXB5 HOXB9 HOXC8 HR HYAL2 ILF2 INCA1 INPP5D ITGB4 KANK2 KPRP KRT20 KRTAP11-1 KRTAP12-2 KRTAP19-2 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP26-1 KRTAP4-4 KRTAP6-1 KRTAP6-2 LAGE3 LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C LCE3A LCE3C LCE3D LCE3E LCE5A LGALS9 LNX1 MAGED1 MAPK1IP1L MAPKBP1 MBD3L2 MED25 MEIS2 MEOX2 MGAT5B NODAL NOTO NR4A3 OLIG3 OTX1 OXER1 P4HB PATZ1 PCDHB14 PGAP6 PHETA1 PHLDA1 PIGS PITX1 PLSCR4 POU4F2 POU4F3 PPP1R32 PPP1R37 PRMT8 PROP1 PRPF31 PRR13 PRR3 PRR35 PSMA1 PVR RAB3IL1 RAD54L2 RASD1 RHBDL1 RUNX1T1 SAMD7 SEMA4C SH3KBP1 SLC15A2 SLC22A5 SMARCC1 SMARCE1 SMCP SNRPB SNRPC SNX18 STK16 STRA6 TAOK2 TBX2 TBX6 TCAF1 TCF7L2 TEKT4 TENT2 TEX45 TFAP2D TLE5 TLX3 TNIP1 TNS2 TSPYL6 TYK2 VASN VENTX VSTM4 WDR25 ZBTB32 ZIC1 ZNF414 ZNF497 ZNF575 ZNF79	6 interacting genes: CALCOCO2 DAZAP2 KRTAP6-3 OR1D2 P4HB PDIA6
Entrez ID		337968	3965
HPRD ID		11220	03528
Ensembl ID		ENSG00000212938	ENSG00000168961
Uniprot IDs			A0A024QZ02 A0A024QZ55 O00182
PDB IDs			2EAK 2EAL 2YY1 2ZHK 2ZHL 2ZHM 2ZHN 3LSD 3LSE 3NV1 3NV2 3NV3 3NV4 3WLU 3WV6
Enriched GO Terms of Interacting Partners?
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