KRTAP7-1 and TFAP2D

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KRTAP7-1	TFAP2D
Description		keratin associated protein 7-1	transcription factor AP-2 delta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Intermediate Filament	Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding
	Biological Process		Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Population Proliferation Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development Inferior Colliculus Development
Pathways			Negative regulation of activity of TFAP2 (AP-2) family transcription factors Negative regulation of activity of TFAP2 (AP-2) family transcription factors Activation of the TFAP2 (AP-2) family of transcription factors
Drugs
Diseases
GWAS			Age at first sexual intercourse ( 34211149) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Body mass index ( 29273807) Breast size ( 22747683) Endometriosis or endometrial cancer (pleiotropy) ( 29608257) Fruit consumption ( 32066663) Hand grip strength ( 29691431) Overweight status ( 25133637) Parahippocampal gyrus volume ( 31530798) Refractive error ( 32231278) Response to citalopram or escitalopram in depression ( 27622933) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Subcutaneous adipose tissue ( 29178545) Systolic blood pressure ( 28135244) Western dietary pattern ( 28644415)
Interacting Genes		37 interacting genes: ARID5A C11orf16 C1orf94 CELF5 CREB5 CRYBA2 DTX2 FAM168A FOXH1 GATA2 GCM2 HGS HNRNPF MKRN3 MYOZ3 OTX1 PITX1 PITX2 PRR13 PSMB1 RANBP3 RHOXF2 RNF38 ROR2 SHARPIN SMARCC1 SNRPC SPAG8 TCF7L2 TEKT4 TFAP2D TLE5 TLX3 TOLLIP VPS37C YTHDF1 ZIC1	64 interacting genes: ADAM12 ADAMTSL4 AGR2 AKAP8L BAG4 CAMK2A CARD10 CDPF1 CEP76 CNFN CSNK2B CYSRT1 FAM166B FAM168A GUCD1 GYS1 HOXD12 IKZF3 INCA1 KLHL20 KPRP KRT31 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP11-1 KRTAP12-3 KRTAP15-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP9-2 KRTAP9-3 MLH1 OIP5 PITX1 PLEKHG4 PRR22 PSMB4 RAD54L2 SIVA1 SLAIN1 SPRY1 SSC4D TEPSIN TEX37 TLE5 TNS2 TRAF1 TRIM42 TSC1 USP54 VPS37C ZBTB32 ZMYND12
Entrez ID		337878	83741
HPRD ID		19546	11627
Ensembl ID		ENSG00000274749	ENSG00000008197
Uniprot IDs		Q8IUC3	Q7Z6R9
PDB IDs
Enriched GO Terms of Interacting Partners?
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