Description |
heat shock protein 90 alpha family class A member 1 |
casein kinase 2 alpha 1 |
Image |
|
|
GO Annotations |
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
- Rifabutin
- Nedocromil
- 9-Butyl-8-(2,5-Dimethoxy-Benzyl)-9h-Purin-6-Ylamine
- Geldanamycin
- 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-2-Fluoro-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine
- 9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine
- 4-(1,3-Benzodioxol-5-Yl)-5-(5-Ethyl-2,4-Dihydroxyphenyl)-2h-Pyrazole-3-Carboxylic Acid
- 8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine
- 8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9-Pent-9h-Purin-6-Ylamine
- 9-Butyl-8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9h-Purin-6-Ylamine
- 4-(1h-Imidazol-4-Yl)-3-(5-Ethyl-2,4-Dihydroxy-Phenyl)-1h-Pyrazole
- 9-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-Amine
- 9-Butyl-8-(4-Methoxybenzyl)-9h-Purin-6-Amine
- 9-Butyl-8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine
- Quercetin
- 8-Benzo[1,3]Dioxol-,5-Ylmethyl-9-Butyl-2-Fluoro-9h-Purin-6-Ylamine
- 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine
- N-[4-(AMINOSULFONYL)BENZYL]-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE
- Tanespimycin
- SNX-5422
- N-(4-ACETYLPHENYL)-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE
- 4-CHLORO-6-(4-{4-[4-(METHYLSULFONYL)BENZYL]PIPERAZIN-1-YL}-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL
- 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE
- 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]isoxazole-3-carboxamide
- 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)ISOXAZOLE-3-CARBOXAMIDE
- 2-amino-4-[2,4-dichloro-5-(2-pyrrolidin-1-ylethoxy)phenyl]-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide
- 4-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL
- (3E)-3-[(phenylamino)methylidene]dihydrofuran-2(3H)-one
- 6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE
- 3-({2-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)ETHYNYL]BENZYL}AMINO)-1,3-OXAZOL-2(3H)-ONE
- N-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)METHYL]-3-{[(E)-(2-OXODIHYDROFURAN-3(2H)-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDE
- 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)-1H-PYRAZOLE-3-CARBOXAMIDE
- 4-bromo-6-(6-hydroxy-1,2-benzisoxazol-3-yl)benzene-1,3-diol
- CCT-018159
- 4-chloro-6-{5-[(2-morpholin-4-ylethyl)amino]-1,2-benzisoxazol-3-yl}benzene-1,3-diol
- 8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE
- 4-methyl-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine
- (5E,7S)-2-amino-7-(4-fluoro-2-pyridin-3-ylphenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one oxime
- 8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H-
- 4-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol
- 2-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triol
- 2-[(2-methoxyethyl)amino]-4-(4-oxo-1,2,3,4-tetrahydro-9H-carbazol-9-yl)benzamide
- 4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine
- 4-(2,4-dichlorophenyl)-5-phenyldiazenyl-pyrimidin-2-amine
- 3,6-DIAMINO-5-CYANO-4-(4-ETHOXYPHENYL)THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
- 2-AMINO-4-(2,4-DICHLOROPHENYL)-N-ETHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE
- Copper
- Polaprezinc
- Alvespimycin
|
- ATP
- (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid
- 1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One
- Resveratrol
- 1,8-Di-Hydroxy-4-Nitro-Anthraquinone
- Benzamidine
- 5,8-Di-Amino-1,4-Dihydroxy-Anthraquinone
- Quercetin
- Phosphoaminophosphonic Acid-Adenylate Ester
- Tetrabromo-2-Benzotriazole
- DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE
- S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE
- N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE
- Emodin
- 3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE
- 19-(cyclopropylamino)-4,6,7,15-tetrahydro-5H-16,1-(azenometheno)-10,14-(metheno)pyrazolo[4,3-o][1,3,9]triazacyclohexadecin-8(9H)-one
- N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE
- 4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
- 2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
- 2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
- 2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
- N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE
- Dichlororibofuranosylbenzimidazole
- Quinalizarin
- Ellagic acid
- Fostamatinib
|
Diseases |
|
|
GWAS |
- Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
|
|
Interacting Genes |
207 interacting genes:
A1BG
A2M
AGT
AHR
AHSA1
AHSA2P
AHSG
AIP
AIPL1
AKT1
AKT2
APAF1
APOA1
APOA4
APOB
APOE
AR
ARNTL
ASGR1
BIRC5
BRMS1
C3
C4A
C4BPA
CACYBP
CALM1
CDC37
CDC37L1
CDK4
CDK5R1
CDKN2A
CERS2
CFB
CFTR
CHEK1
CHORDC1
CHUK
CKS1B
CKS2
COL12A1
CP
CRNKL1
CSNK2A1
CSNK2A2
DAP3
DCD
DNAJC7
EGFR
EGLN1
EIF2AK1
EIF2AK2
EIF2AK3
EIF2S1
EPAS1
EPRS1
ERBB2
ERN1
ESR1
ESRRB
FAM162A
FANCC
FASN
FGA
FKBP1A
FKBP4
FKBP5
FKBP6
FLCN
FLG2
FN1
FNIP1
FYN
GABARAPL1
GC
GNA12
GSK3A
GSK3B
GSN
GUCY1B1
GZMA
HDAC6
HIF1A
HIF3A
HP
HPR
HPX
HRNR
HSF1
HSPA8
HSPG2
HTT
IGHA2
IGHD
IKBKB
IKBKE
IKBKG
IP6K2
IRAK1
IRF3
ITGB1BP2
ITIH1
JUN
JUP
KDR
KEAP1
LCK
LGALS3BP
LINC01554
LOXL2
LRP1
LSM1
MAP3K14
MAP3K3
MAPK1
MAPT
MED28
MIS12
MMP2
MS4A2
MTRNR2L1
MUC1
MYC
MYOD1
NDRG1
NOS1
NOS3
NPAS2
NR2C2
NR3C1
NR3C2
NSL1
OGT
PABPN1
PAK1
PDPK1
PHLDA2
PIM1
PKM
PLG
PMF1
PPARA
PPARD
PPID
PPIL2
PPP5C
PRKACA
PRKCA
PRKCD
PRKDC
PTGDS
PTGES3
PTPRF
RAD51
RAF1
RHOBTB2
RIPK1
RPAP3
RPS3
RPS3A
RUNX1T1
SERPINA1
SERPINA3
SERPINB5
SERPINC1
SERPING1
SGTA
SHKBP1
SIM1
SKP1
SLC2A4
SLC34A1
SMYD2
SMYD3
SNCA
SRC
ST13
STARD13
STAT3
STIP1
STUB1
SUGT1
SUMO2
SVIL
TBK1
TCIRG1
TERT
TF
THBS1
TJP1
TLN1
TNFRSF1A
TOMM34
TOMM40
TOMM70
TP53
TTK
TTR
UBASH3A
UBE2N
UCHL1
UNC45A
USP13
USP19
USP50
WASL
YWHAE
YWHAZ
|
436 interacting genes:
-
ABCA1
ABCC1
ACACA
ACAT2
ACE
ACIN1
AIP
AKAP8
AKT1
ALKBH5
ANP32B
APEX1
APOE
APP
AQP4
ARL6IP4
ARMCX3
ARNT
ARR3
ARRB2
ASIC3
ATF1
ATF2
ATG16L1
ATN1
ATP2B1
ATP5F1A
AUTS2
BCLAF1
BDP1
BEND7
BHLHE41
BID
BIRC6
BMS1
BRCA1
BRF1
BRMS1
C1orf109
C1orf35
C1R
CALM1
CALU
CANX
CARD9
CASP2
CASQ2
CAV1
CAV2
CCDC116
CCDC6
CD2BP2
CD5
CDC25B
CDC37
CDH1
CDK1
CDKN1A
CFDP1
CHD4
CHUK
CIRBP
CLASP2
CLNS1A
CLTB
COPS2
COPS3
COPS7A
CPSF6
CPSF7
CREB3L3
CREBBP
CREM
CSN1S1
CSN2
CSNK2B
CT45A1
CTDP1
CTNNA1
CTNNB1
CUX2
DAXX
DDIT3
DDX17
DDX21
DDX24
DDX3X
DDX54
DEK
DELEC1
DHX16
DHX38
DKC1
DNAJB2
DPF3
DTD1
DVL1
DVL3
ECD
EEF1B2
EEF1D
EGR1
EHMT2
EIF2B5
EIF2S1
EIF2S2
EIF3J
EIF4B
EIF4EBP1
EIF5
EIF5B
ERH
EXOSC9
F11R
F5
FAF1
FAM133A
FBXO28
FCHO1
FGF1
FGF2
FIBP
FIP1L1
FKBP3
FKBP4
FLG
FNBP4
FOS
FTSJ3
FXR1
GABRR1
GABRR2
GANAB
GAP43
GGA1
GMFB
GMNN
GPATCH2
GPATCH2L
GPI
GPN1
GRIN2A
GRIN2B
GSC2
GTF2A1
GTF2A1L
GTF2F1
GYS1
HCLS1
HDAC1
HDAC2
HDAC3
HDGFL2
HDLBP
HES6
HGS
HIF1A
HMGA1
HMGA2
HMOX2
HNRNPA2B1
HNRNPC
HNRNPDL
HNRNPL
HOXB7
HOXC4
HSF1
HSP90AA1
HSP90AB1
HSP90B1
HSPA4
HSPB8
HSPH1
HTATSF1
IFI16
IFRD1
IGF2R
IGFBP3
IL16
INF2
IRF2
IRS1
ITCH
IWS1
JADE2
JUN
KANK2
KDM1A
KEAP1
KIF1C
KIF24
KIF5C
KLF1
KPNA4
L1CAM
LARP1
LEO1
LGALS3
LHX3
LHX8
LHX9
LIG1
LRRC59
LSM14A
LTV1
MAF1
MAGEA11
MAK16
MAPK1
MAPK14
MAPT
MAX
MAZ
MCM2
MCM3
MDC1
MDM2
MEF2C
MEOX1
MEOX2
MFAP1
MGMT
MME
MPHOSPH10
MRPL38
MRPL4
MS4A1
MSH6
MTDH
MUS81
MYB
MYC
MYCN
MYF5
MYH9
NAF1
NAP1L1
NAP1L4
NCAPD2
NCL
NCOR1
NFKBIA
NFKBIB
NFYA
NKX2-5
NMD3
NMT1
NOL3
NOLC1
NOP56
NOP58
NPM1
NRF1
NUP98
NXF1
OCLN
OGDHL
OGT
OSBP
OTUB1
PACS1
PAFAH1B1
PAK1
PAX5
PAX6
PAX7
PDAP1
PDCD4
PDIA6
PGK1
PGR
PHF19
PIAS1
PIN1
PIN4
PIP4K2B
PLEKHO1
PML
PNN
POLR2A
POU6F2
PPAN
PPP1R1B
PPP1R2
PPP1R8
PRCC
PRKACB
PRNP
PRPF38A
PSEN2
PSIP1
PSMA3
PSMA4
PSME3IP1
PTEN
PTPA
PTPN1
PTPRC
PURB
RAD1
RAD51
RAD9A
RANGAP1
RBM10
RBM17
RBM33
RBM39
RBMX
REL
RELA
RGS19
RIOK1
RIOK2
RNF111
RNF7
RPL13
RPL5
RPL6
RPLP0
RPLP1
RPRD2
RPS18
RPS3
RPS6KB1
RRAD
RRP12
RRP1B
RRP9
RSF1
RSL1D1
SAFB
SAP30BP
SAT1
SCNN1A
SEPTIN2
SERBP1
SERPINF1
SF3A1
SF3B1
SF3B2
SFPQ
SHOX
SLC18A2
SLC4A1AP
SLIRP
SMARCC2
SNAI2
SNCA
SND1
SP1
SPATS2L
SPI1
SPIB
SPP1
SPTBN1
SQSTM1
SREK1
SRF
SRRM1
SRRM2
SRRT
SRSF10
SRSF11
SRSF2
SSB
SSRP1
STAC3
STMN1
STX1A
SUB1
SUDS3
SUGT1
SUPT5H
SUPT6H
SURF6
TCF7L2
TCOF1
TEPSIN
TFAP2A
TH
THAP1
THOC5
THRAP3
TLE5
TMOD3
TMPO
TNKS1BP1
TNP1
TOP1
TOP2A
TP53
TP63
TP73
TRIM41
TSPY1
TSPYL2
UBAC1
UBE2D3
UBE2R2
UBTF
USP24
USP48
USP7
UTP14A
UTP18
VAMP4
VDR
VHL
VTN
WAS
WDR44
WDR55
WEE1
XK
XKRY
XRCC1
XRCC4
XRCC5
XRCC6
XRN2
YBX1
YWHAB
YWHAQ
ZC3H13
ZC3H15
ZC3H8
ZFC3H1
ZHX1
ZNF177
ZNF440
ZNF558
ZNF559-ZNF177
ZNF670
ZRANB2
ZSCAN25
|
Entrez ID |
3320 |
1457 |
HPRD ID |
00777 |
00277 |
Ensembl ID |
ENSG00000080824
|
ENSG00000101266
|
Uniprot IDs |
K9JA46
P07900
Q86SX1
|
P68400
|
PDB IDs |
1BYQ
1OSF
1UY6
1UY7
1UY8
1UY9
1UYC
1UYD
1UYE
1UYF
1UYG
1UYH
1UYI
1UYK
1UYL
1YC1
1YC3
1YC4
1YER
1YES
1YET
2BSM
2BT0
2BUG
2BYH
2BYI
2BZ5
2C2L
2CCS
2CCT
2CCU
2FWY
2FWZ
2H55
2JJC
2K5B
2QF6
2QFO
2QG0
2QG2
2UWD
2VCI
2VCJ
2WI1
2WI2
2WI3
2WI4
2WI5
2WI6
2WI7
2XAB
2XDK
2XDL
2XDS
2XDU
2XDX
2XHR
2XHT
2XHX
2XJG
2XJJ
2XJX
2XK2
2YE2
2YE3
2YE4
2YE5
2YE6
2YE7
2YE8
2YE9
2YEA
2YEB
2YEC
2YED
2YEE
2YEF
2YEG
2YEH
2YEI
2YEJ
2YI0
2YI5
2YI6
2YI7
2YJW
2YJX
2YK2
2YK9
2YKB
2YKC
2YKE
2YKI
2YKJ
3B24
3B25
3B26
3B27
3B28
3BM9
3BMY
3D0B
3EKO
3EKR
3FT5
3FT8
3HEK
3HHU
3HYY
3HYZ
3HZ1
3HZ5
3INW
3INX
3K97
3K98
3K99
3MNR
3O0I
3OW6
3OWB
3OWD
3Q6M
3Q6N
3QDD
3QTF
3R4M
3R4N
3R4O
3R4P
3R91
3R92
3RKZ
3RLP
3RLQ
3RLR
3T0H
3T0Z
3T10
3T1K
3T2S
3TUH
3VHA
3VHC
3VHD
3WHA
3WQ9
4AIF
4AWO
4AWP
4AWQ
4B7P
4BQG
4BQJ
4CGQ
4CGU
4CGV
4CGW
4CWF
4CWN
4CWO
4CWP
4CWQ
4CWR
4CWS
4CWT
4EEH
4EFT
4EFU
4EGH
4EGI
4EGK
4FCP
4FCQ
4FCR
4HY6
4JQL
4L8Z
4L90
4L91
4L93
4L94
4LWE
4LWF
4LWG
4LWH
4LWI
4NH7
4NH8
4O04
4O05
4O07
4O09
4O0B
4R3M
4U93
4W7T
4XIP
4XIQ
4XIR
4XIT
4YKQ
4YKR
4YKT
4YKU
4YKW
4YKX
4YKY
4YKZ
5CF0
5FNC
5FND
5FNF
5GGZ
5J20
5J27
5J2V
5J2X
5J64
5J6L
5J6M
5J6N
5J80
5J82
5J86
5J8M
5J8U
5J9X
5LNY
5LNZ
5LO0
5LO1
5LO5
5LO6
5LQ9
5LR1
5LR7
5LRL
5LRZ
5LS1
5M4E
5M4H
5NYH
5NYI
5OCI
5OD7
5ODX
5T21
5VYY
5XQD
5XQE
5XR5
5XR9
5XRB
5XRD
5XRE
5ZR3
6B99
6B9A
6CEO
6CYG
6CYH
6EI5
6EL5
6ELN
6ELO
6ELP
6EY8
6EY9
6EYA
6EYB
6F1N
6FCJ
6FDP
6GP4
6GP8
6GPF
6GPH
6GPO
6GPP
6GPR
6GPT
6GPW
6GPY
6GQ6
6GQR
6GQS
6GQU
6GR1
6GR3
6GR4
6GR5
6HHR
6KSQ
6LR9
6LSZ
6LT8
6LTI
6LTK
6N8X
6OLX
6TN4
6TN5
6U98
6U99
6U9A
6U9B
7LSZ
7LT0
|
1JWH
1NA7
1PJK
2PVR
2ZJW
3AMY
3AT2
3AT3
3AT4
3AXW
3BQC
3C13
3FWQ
3H30
3JUH
3MB6
3MB7
3NGA
3NSZ
3OWJ
3OWK
3OWL
3PE1
3PE2
3PE4
3Q04
3Q9W
3Q9X
3Q9Y
3Q9Z
3QA0
3R0T
3RPS
3TAX
3U4U
3U87
3U9C
3W8L
3WAR
3WIK
3WIL
3WOW
4DGL
4FBX
4GRB
4GUB
4GYW
4GYY
4GZ3
4IB5
4KWP
4MD7
4MD8
4MD9
4NH1
4RLL
4UB7
4UBA
5B0X
5CLP
5CQU
5CQW
5CS6
5CSH
5CSP
5CSV
5CT0
5CTP
5CU0
5CU2
5CU3
5CU4
5CU6
5CVF
5CVG
5CVH
5CX9
5H8B
5H8E
5H8G
5HGV
5KU8
5KWH
5M44
5M4C
5M4F
5M4I
5MMF
5MMR
5MO5
5MO6
5MO7
5MO8
5MOD
5MOE
5MOH
5MOT
5MOV
5MOW
5MP8
5MPJ
5N1V
5N9K
5N9L
5N9N
5NQC
5OMY
5ONI
5OQU
5ORH
5ORJ
5ORK
5OS7
5OS8
5OSL
5OSP
5OSR
5OSU
5OSZ
5OT5
5OT6
5OTD
5OTH
5OTI
5OTL
5OTO
5OTP
5OTQ
5OTR
5OTS
5OTY
5OTZ
5OUE
5OUL
5OUM
5OUU
5OWH
5OWL
5OYF
5T1H
5VIE
5VIF
5ZN0
5ZN1
5ZN2
5ZN3
5ZN4
5ZN5
6A1C
6E37
6EHK
6EHU
6EII
6FVF
6FVG
6GIH
6GMD
6HBN
6HME
6HNW
6HNY
6HOP
6HOQ
6HOR
6HOT
6HOU
6JWA
6L1Z
6L21
6L22
6L24
6Q38
6Q4Q
6QY7
6RB1
6RCB
6RCM
6RFE
6RFF
6SPW
6SPX
6TEI
6TLL
6TLO
6TLP
6TLR
6TLS
6TLU
6TLV
6TLW
6YPG
6YPH
6YPJ
6YPK
6YPN
6YUL
6YUM
6Z83
6Z84
7A49
7A4B
7A4C
7B8H
7B8I
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
|
Tagcloud (Difference) ? |
|
|
Tagcloud (Intersection) ? |
|