HSPB2 and ATP6V1E1

Number of citations of the paper that reports this interaction (PubMedID 26465331)
5

Data Source:
BioGRID (two hybrid)

		HSPB2	ATP6V1E1
Description		heat shock protein family B (small) member 2	ATPase H+ transporting V1 subunit E1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Vacuolar Proton-transporting V-type ATPase, V1 Domain Lysosomal Membrane Endosome Cytosol Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Extracellular Exosome
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Enzyme Activator Activity	Protein Binding Hydrolase Activity Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding
	Biological Process	Response To Unfolded Protein Regulation Of Catalytic Activity	Regulation Of Macroautophagy Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		110 interacting genes: A1CF A2M ABCC9 ABCD4 ACAA2 ACTA1 ACTB ACTC1 ACTG1 AGAP11 ALDH2 ALDOA ASAH1 ATM ATP5F1A ATP6V1E1 B2M BAG3 BEX2 BEX4 BGN BICRAL C1QA CAPZA2 CEP19 CKM CLK4 CMYA5 CRYAA CRYAB CRYGC CTSB CTSD CYP1B1 DCTN1 DCTN6 DDIT4 DDX10 DMPK DUSP1 EEF1A1 EIF4A2 ENKD1 ENO1 ENO3 ETFA FHL2 FLNC GAPDH GARS1 HADHB HNRNPD HOXB9 HSPB3 HSPB8 KANK2 LGALS1 LMO1 LMO3 MAPKAPK5 MB MCCC2 MDH1 MISP MLF2 MT-CO1 MT-CO2 MT-CO3 MYBPC3 MYH6 MYOM2 MYOZ2 NARS1 NDUFA13 NDUFA6 NT5DC2 PARVA PATZ1 PGM1 PKP2 POGZ PPM1K PRR35 RFPL3 RPL11 RPL36A RPL36AL RPS11 RPS6KA5 RYR2 SDF2 SDHA SLC2A1 SNCA SNU13 SNX18 TATDN1 TCAP THEMIS2 THUMPD2 TLX3 TNNI3 TTN TXNIP UBL5 VEZF1 WDR1 WWOX YPEL3 ZNF335	14 interacting genes: ALDOA ALDOB ALDOC APP ATP6V0E1 ATP6V1G1 ATP6V1G2 ATP6V1H HSPB2 MESD SLC9A3R1 SOS1 TRAF6 XRCC6
Entrez ID		3316	529
HPRD ID		03712	00163
Ensembl ID		ENSG00000170276	ENSG00000131100
Uniprot IDs		A8KAH6 Q16082	P36543 Q53Y06
PDB IDs		6F2R	6WLZ 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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