HOXD8 and RCC1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		HOXD8	RCC1
Description		homeobox D8	regulator of chromosome condensation 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Chromosome Cytoplasm Nuclear Membrane Protein-containing Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Chromatin Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding Nucleosome Binding Nucleosomal DNA Binding Histone Binding Sulfate Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Anterior/posterior Axis Specification, Embryo Positive Regulation Of Transcription By RNA Polymerase II Skeletal System Morphogenesis	G1/S Transition Of Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Mitotic Nuclear Membrane Reassembly Regulation Of Mitotic Nuclear Division Viral Process Regulation Of Catalytic Activity Spindle Assembly Cell Division
Pathways			Rev-mediated nuclear export of HIV RNA Nuclear import of Rev protein Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 31152163) Estimated glomerular filtration rate ( 31152163 31015462 30604766) Glomerular filtration rate (creatinine) ( 28452372) Male-pattern baldness ( 28196072) Urate levels ( 31578528)	Night sleep phenotypes ( 27126917) Systolic blood pressure ( 30578418)
Interacting Genes		9 interacting genes: ANXA7 BAIAP2 CDKN1A DYNC1I2 HMGB1 LDLRAP1 NCK2 PFDN1 RCC1	51 interacting genes: ACTB APLP1 BAG6 CCT7 CDK1 CDK2AP2 CHGB CHKA CSAD CSNK1A1 DDAH2 DYNC1I1 ERCC6 FAF1 FBXO7 FLAD1 GNB2 H2AC18 H2AC20 H2BC21 H3C1 HADHB HMGA1 HOXD8 KMT2B KPNA3 KPNA4 LRIF1 NGFR NTMT1 NUDT21 NUP98 OGT PDHB PKM PTMA RAN RANBP1 RANBP3 RPA1 SDF4 SPRED1 SUMO2 TLE1 TRMT2A TUBB3 UNC119 USP4 WIZ XPO1 ZNF135
Entrez ID		3234	1104
HPRD ID		00868	01559
Ensembl ID		ENSG00000175879	ENSG00000180198
Uniprot IDs		A0A0A0MSX5 P13378	A0A0S2Z3I4 A0A0S2Z404 P18754 Q5T081
PDB IDs			1A12 1I2M 5E1B 5E1D 5E1M 5E1O 5E2A 5E2B 5TBK 6DUB
Enriched GO Terms of Interacting Partners?
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