HLA-DRB5 and CTAG1B

Number of citations of the paper that reports this interaction (PubMedID 11782380)
22

Data Source:
HPRD (in vitro)

		HLA-DRB5	CTAG1B
Description		major histocompatibility complex, class II, DR beta 5	cancer/testis antigen 1B
Image
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Plasma Membrane ER To Golgi Transport Vesicle Membrane Transport Vesicle Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Late Endosome Membrane Trans-Golgi Network Membrane MHC Class II Protein Complex Extracellular Exosome Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane	Cytoplasm
	Molecular Function	MHC Class II Protein Complex Binding Peptide Antigen Binding	Protein Binding Identical Protein Binding
	Biological Process	Adaptive Immune Response Immunoglobulin Production Involved In Immunoglobulin-mediated Immune Response Peptide Antigen Assembly With MHC Class II Protein Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of T Cell Activation	TRNA Threonylcarbamoyladenosine Metabolic Process
Pathways		Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules MHC class II antigen presentation PD-1 signaling Interferon gamma signaling
Drugs		1D09C3 Coccidioides immitis spherule
Diseases
GWAS		Acute anterior uveitis (with or without ankylosing spondylitis) ( 25200001) Alzheimer's disease ( 31473137) Alzheimer's disease (late onset) ( 30617256 24162737) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Antinuclear antibody levels ( 25186300) Apolipoprotein A1 levels ( 32203549) Asthma ( 30929738 27182965 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Automobile speeding propensity ( 30643258) Blood protein levels ( 29875488) Body mass index ( 28892062) Bullous pemphigoid ( 34011352) Childhood ear infection ( 27182965) Chronic lymphocytic leukemia ( 21131588 26956414) Crohn's disease ( 23850713) Epstein Barr virus nuclear antigen 1 IgG levels ( 26819262) Frontotemporal dementia ( 24943344) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Heart rate response to exercise ( 29769521) High density lipoprotein cholesterol levels ( 33339817) Hip circumference adjusted for BMI ( 34021172) Hypothyroidism ( 22493691) Immune response to measles vaccine (measles-induced IFN gamma) ( 28289848) Inflammatory bowel disease ( 28067908) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Joint damage in rheumatoid arthritis ( 31596875) Lymphocyte counts ( 32888494) Lymphoma ( 23349640) Mean spheric corpuscular volume ( 32888494) Parkinson's disease ( 21292315 27182965) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Prostate cancer ( 23535732) Refractive error ( 32231278) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Sarcoidosis (non-Lofgren's syndrome) ( 26651848) SjÃ¶gren's syndrome ( 24097066) Triglyceride levels ( 32203549) Tuberculosis ( 29036319) Type 2 diabetes ( 28869590) Ulcerative colitis ( 28067908 21297633 19122664) Vogt-Koyanagi-Harada syndrome ( 25108386) Waist-to-hip ratio adjusted for body mass index ( 26785701)
Interacting Genes		3 interacting genes: CTAG1B FXR1 HLA-DRA	82 interacting genes: ACTN3 ALOX15B ARHGEF28 ATP1A4 ATP6AP1 BAG6 BEX1 BEX2 BMF BORCS8 BORCS8-MEF2B C14orf119 C1orf109 CAMSAP1 CCDC116 CCHCR1 CDC37 CDKN2AIPNL CHCHD2 CSTF2T CTAG1A CYTH4 DESI1 FCHSD2 FSD2 GATC GNG13 GPSM3 GTF2I GUCD1 HCK HEMK1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 KIF26A KLHL38 LAMTOR1 LNPEP LONRF3 MAGEC1 MEIS2 MGAT5B MSGN1 NAB2 NCS1 NTAQ1 P4HA3 PEF1 PIH1D2 POLM PSMB1 RANBP10 REX1BD RSRC2 RTN4IP1 RUSC1 SEC14L4 SGTA SGTB SIKE1 SMG9 SOHLH1 SPAG8 STRA8 SUOX TCEANC TEPSIN THOC1 TNPO2 TRIB3 TRIM55 TRIM63 TSGA10IP UBE2V1 UBL5 UBQLN1 UBQLN2 USP20 VENTX WWOX
Entrez ID		3127	1485
HPRD ID		09209	02151
Ensembl ID		ENSG00000198502	ENSG00000184033
Uniprot IDs		A0A2Z4LKS3 Q30154	P78358
PDB IDs		1FV1 1H15 1HQR 1ZGL	1S9W 2BNQ 2BNR 2F53 2F54 2P5E 2P5W 2PYE 3GJF 3HAE 3KLA 6AT5 6AVF 6AVG 6RP9 6RPA 6RPB
Enriched GO Terms of Interacting Partners?
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