ANXA6 and S100A1

Number of citations of the paper that reports this interaction (PubMedID 9883272)
10

Data Source:
HPRD (in vitro)

		ANXA6	S100A1
Description		annexin A6	S100 calcium binding protein A1
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Lysosomal Membrane Focal Adhesion Membrane Late Endosome Membrane Melanosome Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome	Extracellular Region Nucleus Nucleoplasm Cytoplasm Mitochondrion Golgi Apparatus Cytosol Sarcoplasmic Reticulum Z Disc M Band Protein-containing Complex Neuron Projection
	Molecular Function	Phosphatidylserine Binding Calcium Channel Activity Calcium Ion Binding Protein Binding GTP Binding Calcium-dependent Phospholipid Binding Lipid Binding Ligand-gated Ion Channel Activity Cholesterol Binding Chondroitin Sulfate Binding Identical Protein Binding Calcium-dependent Protein Binding Actin Filament Binding	Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding ATPase Binding
	Biological Process	Neural Crest Cell Migration Plasma Membrane Repair Growth Plate Cartilage Chondrocyte Differentiation Regulation Of Muscle Contraction Ion Transmembrane Transport Negative Regulation Of Sequestering Of Calcium Ion Mitochondrial Calcium Ion Homeostasis Calcium Ion Transmembrane Transport Apoptotic Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Heart Contraction Substantia Nigra Development Intracellular Signal Transduction Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Sprouting Angiogenesis
Pathways		Smooth Muscle Contraction	ER-Phagosome pathway MyD88:MAL(TIRAP) cascade initiated on plasma membrane MyD88 deficiency (TLR2/4) IRAK4 deficiency (TLR2/4) Regulation of TLR by endogenous ligand
Drugs			Olopatadine
Diseases
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Inflammatory skin disease ( 25574825) Lymphocyte counts ( 32888494) Psoriasis ( 25903422 25574825) Psoriatic arthritis ( 26626624)
Interacting Genes		17 interacting genes: A2M CDC73 CR2 ERBB2 IL16 LINC01554 LMNA MLH1 MTNR1B OGT RASA1 RHOU S100A1 S100B SMURF1 SNCA TPD52	31 interacting genes: ACTA1 AGER ANXA6 ATP2A2 BEX3 BIK CACYBP CAPZA1 CEP20 DES FKBP4 GFAP GJA1 MDM2 NIF3L1 PGM1 PLB1 PLEKHF2 PLN PPID PYGM REL RYR1 S100A2 S100A3 S100A4 S100B S100P S100Z SYN1 TP53
Entrez ID		309	6271
HPRD ID		00231	01489
Ensembl ID		ENSG00000197043	ENSG00000160678
Uniprot IDs		A0A0S2Z2Z6 P08133	A0A0S2Z4H2 P23297
PDB IDs		1M9I	2L0P 2LHL 2LLS 2LLT 2LLU 2LP2 2LP3 2LUX 2M3W 5K89
Enriched GO Terms of Interacting Partners?
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