KCNIP1 and AMPD3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KCNIP1	AMPD3
Description		potassium voltage-gated channel interacting protein 1	adenosine monophosphate deaminase 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Dendrite Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Extracellular Region Cytosol Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Voltage-gated Ion Channel Activity Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity	AMP Deaminase Activity Protein Binding Metal Ion Binding
	Biological Process	Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport	IMP Biosynthetic Process AMP Catabolic Process IMP Salvage AMP Metabolic Process
Pathways		Phase 1 - inactivation of fast Na+ channels	Neutrophil degranulation Purine salvage
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) California verbal learning test score ( 31596458) Liver transplant-free survival in primary sclerosing cholangitis (time to event) ( 28779025) Normalized brain volume ( 19010793) Placental abruption ( 29884306) Pre-treatment viral load in HIV-1 infection ( 31219150) Short-term memory (digit-span task) ( 30741946)	Apolipoprotein A1 levels ( 32203549) Cutaneous melanoma or hair colour ( 32341527) Diastolic blood pressure ( 27841878) Glycated hemoglobin levels ( 34059833) Haemorrhoidal disease ( 33888516) HDL cholesterol ( 24097068 20686565) HDL cholesterol levels ( 32203549 28334899) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Neutrophil percentage of white cells ( 32888494) Nonunion in individuals with fractures ( 30680360) Pulse pressure ( 27841878) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure ( 27841878) Total cholesterol levels ( 30498476) Waist-hip index ( 34021172) White blood cell count ( 32888494)
Interacting Genes		16 interacting genes: AMPD3 ASPH CIAO2A DAAM2 IL6ST KCND1 KCND2 KCND3 KCNIP2 LITAF NHLH2 NIF3L1 SOD3 SPP1 SPRED2 TBC1D25	2 interacting genes: AMPD1 KCNIP1
Entrez ID		30820	272
HPRD ID		06879	00041
Ensembl ID		ENSG00000182132	ENSG00000133805
Uniprot IDs		Q9NZI2	Q01432
PDB IDs		1S1E 2I2R 2NZ0
Enriched GO Terms of Interacting Partners?
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