ERVW-1 and SLC1A4

Number of citations of the paper that reports this interaction (PubMedID 12050356)
61

Data Source:
HPRD (in vitro, in vivo)

		ERVW-1	SLC1A4
Description		endogenous retrovirus group W member 1, envelope	solute carrier family 1 member 4
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Centrosome Intermediate Filament Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Dendrite Melanosome Neuronal Cell Body Synapse Extracellular Exosome
	Molecular Function		Chloride Channel Activity Amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-aspartate Transmembrane Transporter Activity L-cystine Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity L-proline Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity L-threonine Transmembrane Transporter Activity Symporter Activity L-hydroxyproline Transmembrane Transporter Activity
	Biological Process	Syncytium Formation By Plasma Membrane Fusion Syncytium Formation Myoblast Fusion Anatomical Structure Morphogenesis	Amino Acid Transport Glutamine Transport Inorganic Anion Transport L-alanine Transport L-cystine Transport Proline Transport L-serine Transport Threonine Transport Hydroxyproline Transport Synaptic Transmission, Glutamatergic Proline Transmembrane Transport Cognition L-aspartate Import Across Plasma Membrane Transport Across Blood-brain Barrier L-serine Import Across Plasma Membrane L-alanine Import Across Plasma Membrane
Pathways			Amino acid transport across the plasma membrane
Drugs			Alanine
Diseases
GWAS			Atrial fibrillation ( 28416822) Blood metabolite levels ( 24816252) Ejection fraction ( 29403010) Fractional shortening ( 29403010) Left ventricular internal dimension in systole ( 29403010) Macular telangiectasia type 2 ( 33654266) Metabolite levels ( 22286219 22916037) Metabolite levels (small molecules and protein measures) ( 27005778) Pulse pressure ( 27841878) Serum metabolite levels ( 33031748) Systolic blood pressure ( 27841878) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		2 interacting genes: SLC1A4 SLC1A5	3 interacting genes: CREBBP ERVW-1 F2RL1
Entrez ID		30816	6509
HPRD ID		05231	02576
Ensembl ID		ENSG00000242950	ENSG00000115902
Uniprot IDs		D0EYG5 Q9UQF0	P43007
PDB IDs		5HA6 6RX1
Enriched GO Terms of Interacting Partners?
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