GUCY2D and S100B

Number of citations of the paper that reports this interaction (PubMedID 15556616)
10

Data Source:
HPRD (in vivo)

		GUCY2D	S100B
Description		guanylate cyclase 2D, retinal	S100 calcium binding protein B
Image
GO Annotations	Cellular Component	Photoreceptor Outer Segment Nuclear Outer Membrane Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Photoreceptor Outer Segment Membrane Photoreceptor Disc Membrane	Ruffle Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Neuronal Cell Body Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Peptide Receptor Activity Guanylate Cyclase Activity Protein Kinase Activity Protein Binding ATP Binding GTP Binding Signaling Receptor Activity Protein Homodimerization Activity	Calcium Ion Binding Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Tau Protein Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	CGMP Biosynthetic Process Protein Phosphorylation Signal Transduction Receptor Guanylyl Cyclase Signaling Pathway Visual Perception Regulation Of Rhodopsin Mediated Signaling Pathway Intracellular Signal Transduction	Axonogenesis Central Nervous System Development Learning Or Memory Memory Positive Regulation Of Cell Population Proliferation Regulation Of Cell Shape Positive Regulation Of Myelination Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Neuronal Synaptic Plasticity Astrocyte Differentiation Response To Glucocorticoid Response To Methylmercury Long-term Synaptic Potentiation Cellular Response To Hypoxia Negative Regulation Of Skeletal Muscle Cell Differentiation
Pathways		Inactivation, recovery and regulation of the phototransduction cascade	Nuclear signaling by ERBB4 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Advanced glycosylation endproduct receptor signaling Advanced glycosylation endproduct receptor signaling TRAF6 mediated NF-kB activation
Drugs			Olopatadine Calcium N-Formylmethionine Arundic acid (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide 2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Refractive error ( 32231278)	Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921) Cutaneous leishmaniasis ( 32830257) Lymphocyte counts ( 22286170)
Interacting Genes		5 interacting genes: GUCA1A GUCA1B GUCA2B RGS9 S100B	47 interacting genes: ADTRP AGER AGTRAP AHNAK ANXA6 BCL2L2 CACYBP CALM1 CAPZA1 CEP20 CT45A5 DES DNAJC30 FBXO7 FBXW5 GFAP GUCY2D IMP4 IMPA1 IQGAP1 LDAF1 LNX1 MAL2 MAPT MDM2 MDM4 NDRG1 NKAPD1 PCNT PGM1 RABAC1 S100A1 S100A11 S100A2 S100A4 S100A6 S100A9 S100P S100Z SDCBP SPG21 STK38 SUGT1 TMEM239 TNIP1 TP53 VAV1
Entrez ID		3000	6285
HPRD ID		02550	01505
Ensembl ID		ENSG00000132518	ENSG00000160307
Uniprot IDs		Q02846	A0A0S2Z4C5 P04271
PDB IDs		1AWL	1MQ1 1UWO 2H61 2M49 2PRU 3CZT 3D0Y 3D10 3HCM 4XYN 5CSF 5CSI 5CSJ 5CSN 5D7F
Enriched GO Terms of Interacting Partners?
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