LMCD1 and PRKAG3

Number of citations of the paper that reports this interaction (PubMedID 19616115)
11

Data Source:
BioGRID (two hybrid)

		LMCD1	PRKAG3
Description		LIM and cysteine rich domains 1	protein kinase AMP-activated non-catalytic subunit gamma 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Nucleotide-activated Protein Kinase Complex
	Molecular Function	Transcription Corepressor Activity Protein Binding Zinc Ion Binding	AMP-activated Protein Kinase Activity Protein Binding ATP Binding AMP Binding Protein Kinase Regulator Activity Protein Kinase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Calcineurin-NFAT Signaling Cascade	Glycogen Biosynthetic Process Glycolytic Process Protein Phosphorylation Fatty Acid Biosynthetic Process Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Intracellular Signal Transduction Cellular Response To Glucose Starvation Regulation Of Catalytic Activity Regulation Of Protein Serine/threonine Kinase Activity
Pathways		Surfactant metabolism	Translocation of SLC2A4 (GLUT4) to the plasma membrane Macroautophagy Activation of PPARGC1A (PGC-1alpha) by phosphorylation Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of TP53 Activity through Phosphorylation Lipophagy Activation of AMPK downstream of NMDARs
Drugs			Adenosine phosphate Acetylsalicylic acid Fostamatinib
Diseases
GWAS		Brain volume in infants (intracranial brain volume) ( 28763065) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Low high density lipoprotein cholesterol levels ( 26879886) Metabolite levels ( 23823483) Mitral valve prolapse ( 26301497) Platelet count ( 32888494) Plateletcrit ( 32888494) Rumination (response to stress) ( 30886212) Uterine fibroid number (single vs multiple) ( 30196971)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol ( 25961943) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 33339817) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Male-pattern baldness ( 28196072) Triglyceride levels ( 32203549 33339817)
Interacting Genes		9 interacting genes: APP FBXO25 IKBKG NKX3-1 PRKAG3 RABIF TEKT4 TRIM55 TRIM63	6 interacting genes: BRCA1 CRYAB KRTAP19-5 LMCD1 NGRN PRKAA1
Entrez ID		29995	53632
HPRD ID		06891	16085
Ensembl ID		ENSG00000071282	ENSG00000115592
Uniprot IDs		B4DEY6 B7Z6R5 H7C3D2 Q9NZU5	Q9UGI9
PDB IDs
Enriched GO Terms of Interacting Partners?
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