SEC61A1 and SLC13A1

Number of citations of the paper that reports this interaction (PubMedID 18407958)
29

Data Source:
BioGRID (protein complementation assay)

		SEC61A1	SLC13A1
Description		SEC61 translocon subunit alpha 1	solute carrier family 13 member 1
Image			No pdb structure
GO Annotations	Cellular Component	Sec61 Translocon Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Signal Sequence Binding Calcium Channel Activity Protein Binding Protein Transmembrane Transporter Activity Ribosome Binding	Sodium:sulfate Symporter Activity
	Biological Process	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organization Posttranslational Protein Targeting To Membrane, Translocation Response To Interferon-gamma Pronephric Nephron Development Protein Targeting To ER Calcium Ion Transmembrane Transport	Sodium Ion Transport Sulfate Transport Anion Transmembrane Transport Sulfate Transmembrane Transport
Pathways		ER-Phagosome pathway SRP-dependent cotranslational protein targeting to membrane	Sodium-coupled sulphate, di- and tri-carboxylate transporters
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Gestational age at birth (maternal effect) ( 28877031)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel) ( 23648065) High density lipoprotein cholesterol levels ( 30498476) Systolic blood pressure ( 30578418)
Interacting Genes		12 interacting genes: ACAD9 BAG6 CALM1 GET3 HSPA5 MLH1 PLXND1 PTEN SEC61G SERP1 SLC13A1 TNF	31 interacting genes: ACOT2 ACTR10 APLP2 ARL6IP1 ASS1 CD59 COQ5 COQ9 CRYAB DYNLL1 FTL GRN HSPA1A MKRN1 NDUFS5 OGDHL PDZK1 PNPLA6 PRSS8 RHOA SDHD SEC61A1 SELPLG SERPINA1 SLC9A3R1 SLC9A3R2 TBRG1 TM4SF1 TMED10 TP53I11 TSPAN3
Entrez ID		29927	6561
HPRD ID		15316	08394
Ensembl ID		ENSG00000058262	ENSG00000081800
Uniprot IDs		B3KME8 B3KNF6 P61619	A4D0X1 Q2NKK0 Q9BZW2
PDB IDs		6W6L
Enriched GO Terms of Interacting Partners?
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