SNX11 and SMYD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SNX11	SMYD2
Description		sorting nexin 11	SET and MYND domain containing 2
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GO Annotations	Cellular Component	Endosome Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Phosphatidylinositol Phosphate Binding	RNA Polymerase II Complex Binding P53 Binding Protein Binding Lysine N-methyltransferase Activity Protein-lysine N-methyltransferase Activity Histone-lysine N-methyltransferase Activity Metal Ion Binding Histone Methyltransferase Activity (H3-K36 Specific)
	Biological Process	Intracellular Protein Transport Vesicle Organization	Negative Regulation Of Transcription By RNA Polymerase II Heart Development Negative Regulation Of Cell Population Proliferation Histone H3-K36 Methylation Peptidyl-lysine Monomethylation Peptidyl-lysine Dimethylation Histone Lysine Methylation Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Signal Transduction By P53 Class Mediator
Pathways			PKMTs methylate histone lysines Regulation of TP53 Activity through Methylation
Drugs
Diseases
GWAS		Body mass index ( 26426971) Generalized epilepsy ( 22949513) Triglyceride levels ( 32203549 32154731)	Abdominal aortic aneurysm ( 27899403) Age at first sexual intercourse ( 34211149) Diverticular disease ( 30177863) Rheumatic heart disease ( 34106200) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		10 interacting genes: ARL6IP1 MAJIN NECAB1 RABAC1 REEP6 RPRM SMYD1 SMYD2 YIF1A ZMYND10	7 interacting genes: BTF3L4 ESR1 H3C14 HSP90AA1 RB1 SNX11 TP53
Entrez ID		29916	56950
HPRD ID		15410	15406
Ensembl ID		ENSG00000002919	ENSG00000143499
Uniprot IDs		Q9Y5W9	Q9NRG4
PDB IDs		4IKB 4IKD 6KOI 6KOJ 6KOK	3RIB 3S7B 3S7D 3S7F 3S7J 3TG4 3TG5 4O6F 4WUY 4YND 5ARF 5ARG 5KJK 5KJL 5KJM 5KJN 5V3H 5WCG 6CBX 6CBY 6MON 6N3G
Enriched GO Terms of Interacting Partners?
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