ICOS and NUFIP2

Number of citations of the paper that reports this interaction (PubMedID 29352114)
12

Data Source:
BioGRID (unspecified method)

		ICOS	NUFIP2
Description		inducible T cell costimulator	nuclear FMR1 interacting protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane Nuclear Body Polysomal Ribosome
	Molecular Function	Protein Binding	RNA Binding Protein Binding
	Biological Process	T Cell Tolerance Induction Immune Response T Cell Costimulation Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		Alopecia areata ( 20596022 25608926) Aluminium levels ( 26025379) Body mass index ( 28892062) Celiac disease ( 20190752) Diastolic blood pressure ( 30224653) Hypothyroidism ( 27182965) Idiopathic dilated cardiomyopathy ( 29495422) Inflammatory bowel disease ( 26192919) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Primary biliary cholangitis ( 28425483) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Ulcerative colitis ( 26192919)	Age at first birth ( 34211149) Apolipoprotein B levels ( 32203549) Depression ( 29700475) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Fasting glucose ( 34059833) Headache ( 29397368) Heel bone mineral density ( 30598549) White blood cell count ( 32888494)
Interacting Genes		9 interacting genes: ABI2 ADAM23 BRCC3 ICOSLG NIF3L1 NUFIP2 RC3H1 TNP1 WIF1	131 interacting genes: ADAMTSL4 ADAP2 AGRN AMOT CHRD COMP CRELD1 CRK CYSRT1 DKK3 EFEMP1 EFEMP2 EGFL7 ESM1 FBLN1 FBLN2 FBLN5 FHL5 FMR1 FUCA2 GAPDH GRN HNRNPC ICOS KPRP KRT31 KRT37 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1B LCE2C LCE2D LGALS13 LTBP3 LTBP4 LYZL6 MDFI MEGF11 MEGF6 MIR1-1 MIR106B MIR107 MIR128-1 MIR128-2 MIR138-2 MIR15B MIR17 MIR18A MIR19A MIR200C MIR205 MIR20B MIR21 MIR214 MIR25 MIR31 MIR34A MIR34B MIR363 MIR7-1 MIR7-2 MIR7-3 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NDUFA4L2 NELL1 NOTCH2NLA NOTCH3 OGT PCSK5 PEAR1 PEX5 PHF12 PRDX5 RGS17 RGS19 RGS20 SLC22A17 SPRY2 STAB1 STAT3 STMN4 SYNPO TAOK1 TMOD4 TNFRSF4 TRAF1 TRIM55 TRIM63 VWCE VWF YPEL3 YWHAG
Entrez ID		29851	57532
HPRD ID		09196	11764
Ensembl ID		ENSG00000163600	ENSG00000108256
Uniprot IDs		Q53QY6 Q9Y6W8	Q7Z417
PDB IDs		6X4G 7JOO
Enriched GO Terms of Interacting Partners?
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