GUCA2A and SLC34A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GUCA2A	SLC34A2
Description		guanylate cyclase activator 2A	solute carrier family 34 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Plasma Membrane Integral Component Of Plasma Membrane Brush Border Integral Component Of Membrane Apical Plasma Membrane Brush Border Membrane Vesicle
	Molecular Function	Hormone Activity Protein Binding Guanylate Cyclase Activator Activity	Sodium:phosphate Symporter Activity Sodium Ion Binding Phosphate Ion Binding
	Biological Process	Signal Transduction Positive Regulation Of Guanylate Cyclase Activity	In Utero Embryonic Development Phosphate Ion Transport Cellular Phosphate Ion Homeostasis Sodium Ion Transmembrane Transport Response To Estrogen Cellular Protein Metabolic Process Sodium-dependent Phosphate Transport
Pathways		Digestion	Type II Na+/Pi cotransporters Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) Surfactant metabolism Defective SLC34A2 causes PALM
Drugs
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		15 interacting genes: ASPH FFAR2 GJA8 GOLM1 GUCY2C NEMP1 SGTA SLC34A2 TMEM179B TMEM237 TMEM31 TMEM86B TRAM1 UBQLN1 UBQLN2	19 interacting genes: AIG1 ERG28 FXYD6-FXYD2 GUCA2A JAGN1 LHFPL5 PLN PNLIPRP1 RTP2 SLC30A3 SLC35A1 SLC39A7 STRIT1 TEX264 TMEM128 TMEM239 TMEM42 TRARG1 TSPO2
Entrez ID		2980	10568
HPRD ID		00767	07251
Ensembl ID		ENSG00000197273	ENSG00000157765
Uniprot IDs		Q02747	O95436
PDB IDs		1GNA 1GNB 1O8R
Enriched GO Terms of Interacting Partners?
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