ABT1 and TSPYL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ABT1	TSPYL2
Description		activator of basal transcription 1	TSPY like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding	RDNA Binding Chromatin Binding Protein Binding Histone Binding
	Biological Process	Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage To Generate Mature 5'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Transcription By RNA Polymerase II Small-subunit Processome Assembly Positive Regulation Of Transcription, DNA-templated	Nucleosome Assembly Cell Cycle Negative Regulation Of DNA Replication Regulation Of Signal Transduction Negative Regulation Of Cell Growth Negative Regulation Of Cell Cycle Regulation Of Protein Kinase Activity
Pathways			XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Body shape index ( 34021172) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) General cognitive ability ( 29844566) Hip circumference adjusted for BMI ( 34021172) Intelligence (MTAG) ( 29326435) Left-handedness ( 32989287) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Small cell lung carcinoma ( 28604730) Subcortical volume (MOSTest) ( 32665545) Waist circumference variance ( 31453325) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		16 interacting genes: APP CCDC136 CDCA7L CEP70 DVL3 EMD FAM9B LZTS2 MAB21L3 PICK1 PPP1CC PRNP RNF151 SYNE4 TBP TSPYL2	46 interacting genes: ABT1 AEBP2 APTX CASK CCNB1 CDK1 CDK2 CDK4 CEP19 COIL CREBBP CSNK2A1 EEF1A1 GFI1B H2BC15 HMGXB4 INO80B KMT5B LMO2 LNX1 MCRS1 NOL12 NOP53 PHF19 RBM15 RNF151 RPS25 SIRT6 SNIP1 TBC1D26 TMA16 TNNT1 TSPYL1 XAGE1A XAGE1B ZBTB24 ZBTB48 ZFP1 ZFP91 ZNF280C ZNF286A ZNF329 ZNF524 ZNF687 ZNF775 ZNF835
Entrez ID		29777	64061
HPRD ID		16469	06713
Ensembl ID		ENSG00000146109	ENSG00000184205
Uniprot IDs		A0A024R029 Q9ULW3	Q9H2G4
PDB IDs
Enriched GO Terms of Interacting Partners?
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