GSTA1 and ST3GAL1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		GSTA1	ST3GAL1
Description		glutathione S-transferase alpha 1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Golgi Membrane Membrane Integral Component Of Membrane Trans-Golgi Network Membrane Extracellular Exosome Golgi Medial Cisterna Membrane Golgi Trans Cisterna Membrane
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Steroid Delta-isomerase Activity Fatty Acid Binding	Beta-galactoside (CMP) Alpha-2,3-sialyltransferase Activity Sialyltransferase Activity Monosialoganglioside Sialyltransferase Activity
	Biological Process	Prostaglandin Metabolic Process Glutathione Metabolic Process Xenobiotic Metabolic Process Epithelial Cell Differentiation Linoleic Acid Metabolic Process Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process	Memory B Cell Differentiation N-acetylneuraminate Metabolic Process Cellular Protein Modification Process Protein Phosphorylation Protein N-linked Glycosylation Ganglioside Biosynthetic Process Via Lactosylceramide O-glycan Processing Keratan Sulfate Biosynthetic Process Viral Protein Processing Sialylation Negative Regulation Of Activated CD8-positive, Alpha-beta T Cell Apoptotic Process Protein Sialylation
Pathways		Glutathione conjugation Heme degradation	Keratan sulfate biosynthesis Sialic acid metabolism Maturation of protein 3a Maturation of spike protein Maturation of protein 3a Termination of O-glycan biosynthesis
Drugs		Glutathione S-Hydroxycysteine 2-Hydroxyethyl Disulfide N-(4-Aminobutanoyl)-S-(4-methoxybenzyl)-L-cysteinylglycine Glutathione sulfonic acid Glutathione disulfide S-benzylglutathione S-Hexylglutathione Hypericin
Diseases
GWAS		Blood protein levels ( 29875488) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Serum alkaline phosphatase levels ( 33547301) Triglyceride levels ( 33339817)	Aspartate aminotransferase levels ( 33547301) Blood protein levels ( 30072576 29875488) Frontal fibrosing alopecia ( 30850646) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Intraocular pressure ( 24002674) Personality dimensions ( 23903073) Problematic alcohol use in trauma-exposed individuals ( 29082582) Response to protease inhibitor treatment in hepatitis c (peak serum total bilirubin levels) ( 24503447) Schizophrenia (negative symptoms) ( 23382809) Squamous cell carcinoma ( 26908436)
Interacting Genes		7 interacting genes: APP GSTA2 LSM3 PPP2CB RPAIN ST3GAL1 YWHAE	2 interacting genes: DNAAF11 GSTA1
Entrez ID		2938	6482
HPRD ID		00708	06219
Ensembl ID		ENSG00000243955	ENSG00000008513
Uniprot IDs		A0A140VJK4 B7Z1F9 P08263	A0A024R9L6 Q11201
PDB IDs		1GSD 1GSE 1GSF 1GUH 1K3L 1K3O 1K3Y 1LBK 1PKW 1PKZ 1PL1 1PL2 1USB 1XWG 1YDK 2R3X 2R6K 3I69 3I6A 3IK9 3KTL 3L0H 3Q74 3U6V 3ZFB 3ZFL 4HJ2 5JCU 5LCZ 5LD0 6ATO 6ATP 6ATQ 6ATR 6YAW
Enriched GO Terms of Interacting Partners?
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