GSC2 and ETFDH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GSC2	ETFDH
Description		goosecoid homeobox 2	electron transfer flavoprotein dehydrogenase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Mitochondrial Matrix Integral Component Of Mitochondrial Inner Membrane Mitochondrial Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Electron-transferring-flavoprotein Dehydrogenase Activity Protein Binding Electron Transfer Activity Oxidoreductase Activity Metal Ion Binding Quinone Binding Ubiquinone Binding Flavin Adenine Dinucleotide Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis	Response To Oxidative Stress Electron Transport Chain Respiratory Electron Transport Chain Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase
Pathways			Respiratory electron transport
Drugs			Metformin 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
Diseases
GWAS		Metabolite levels ( 22916037)	Acylcarnitine levels ( 26068415) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Blood protein levels ( 28240269) Metabolic traits ( 21886157) Metabolite levels ( 31628463 20037589) Serum metabolite levels ( 33031748 23093944)
Interacting Genes		61 interacting genes: ALPP ANXA5 ASPH BEST3 BNIP2 C19orf47 C1D CALM1 CALM2 CALM3 CALR CDKN2D CIAO2A COL8A1 CRCP CSNK2A1 DYRK1B EGLN3 EIF5A ETFDH FAM221B FKBP6 GALNT11 GCM2 GTF2H5 GTSF1L GUCA1A GUCY1A2 HMBOX1 ISX KDM6A KLHL38 KRT34 KRTAP5-9 LCE3E LTO1 MAD2L2 MAPK9 MARF1 MID2 MORF4L1 MRPL53 MRPS23 NME7 PACSIN2 PDE4C PRKAB2 PRODH PTER RNF4 SCAF1 SDCBP TIPIN TNPO2 TSR2 UBE2R2 VCX2 XRCC4 YPEL5 ZNF444 ZNF587	9 interacting genes: CLCN3 GSC2 HSD17B10 KRTAP11-1 KRTAP13-2 MYH7B OTX1 TRIM69 ZNF581
Entrez ID		2928	2110
HPRD ID		03506	01978
Ensembl ID		ENSG00000063515	ENSG00000171503
Uniprot IDs		O15499	B4DEQ0 Q16134
PDB IDs
Enriched GO Terms of Interacting Partners?
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