GRM1 and CABIN1

Number of citations of the paper that reports this interaction (PubMedID 19717561)
10

Data Source:
BioGRID (pull down)

		GRM1	CABIN1
Description		glutamate metabotropic receptor 1	calcineurin binding protein 1
Image
GO Annotations	Cellular Component	Nucleus Plasma Membrane Integral Component Of Plasma Membrane Dendrite G Protein-coupled Receptor Dimeric Complex G Protein-coupled Receptor Homodimeric Complex Schaffer Collateral - CA1 Synapse Postsynaptic Density Membrane Glutamatergic Synapse	Nucleus Nucleoplasm Cytosol Aggresome
	Molecular Function	Adenylate Cyclase Inhibiting G Protein-coupled Glutamate Receptor Activity G Protein-coupled Receptor Activity Protein Binding Glutamate Receptor Activity G Protein-coupled Neurotransmitter Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration G Protein-coupled Receptor Activity Involved In Regulation Of Postsynaptic Membrane Potential Neurotransmitter Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration	Protein Phosphatase Inhibitor Activity Protein Binding Nucleosome Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway G Protein-coupled Glutamate Receptor Signaling Pathway Chemical Synaptic Transmission Locomotory Behavior Sensory Perception Of Pain Positive Regulation Of MAPK Cascade Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Regulation Of Sensory Perception Of Pain Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Postsynaptic Membrane Potential Cellular Response To Electrical Stimulus L-glutamate Import Across Plasma Membrane Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration	DNA Replication-independent Nucleosome Assembly Cell Surface Receptor Signaling Pathway Negative Regulation Of Catalytic Activity
Pathways		G alpha (q) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors) Neurexins and neuroligins Neurexins and neuroligins	Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs		Glutamic acid (S)-alpha-methyl-4-carboxyphenylglycine
Diseases
GWAS		Cerebral amyloid deposition (PET imaging) ( 26252872) Suicide ( 31476763) Waist circumference ( 29212154)	Acne (severe) ( 24927181) Amyotrophic lateral sclerosis ( 23624525) Coronary artery disease ( 29212778) Monocyte count ( 32888494) S-phenylmercapturic acid levels in smokers ( 26959369) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		40 interacting genes: ADORA1 BECN1 CABIN1 CASR CCND2 CCNE1 CD44 CDK4 CDK6 CDKN2B CDKN2C EFNB2 EPB41L2 EPHA2 ERBB2 FGFR4 GAPDH GPRASP1 GRK2 HOMER1 HOMER2 IGF1R ITPR1 KAT2A KDELR2 LATS2 MAP2K5 MYC NF2 OPRM1 OPTN PDGFRA PRKCA RAF1 RASSF1 STK11 TAMALIN TERT TTYH2 TUBB	13 interacting genes: AMPH BORCS8-MEF2B CALM1 CAMK4 DNM1 GRM1 HDAC2 MEF2B MEF2D PPP3CA PPP3CB PPP3CC YWHAQ
Entrez ID		2911	23523
HPRD ID		05129	10369
Ensembl ID		ENSG00000152822	ENSG00000099991
Uniprot IDs		Q13255 Q59HC2	A0A024R1E5 A0A087WWW8 Q9Y6J0
PDB IDs		3KS9 4OR2	1N6J
Enriched GO Terms of Interacting Partners?
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