FHOD1 and BBS2

Number of citations of the paper that reports this interaction (PubMedID 18000879)
7

Data Source:
BioGRID (two hybrid)

		FHOD1	BBS2
Description		formin homology 2 domain containing 1	Bardet-Biedl syndrome 2
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Intercalated Disc Membrane Bleb	Cytosol Membrane Motile Cilium BBSome Ciliary Basal Body Neuron Projection Ciliary Membrane
	Molecular Function	Protein Binding Protein Domain Specific Binding Identical Protein Binding Protein Self-association Actin Filament Binding	Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Nuclear Migration Cortical Actin Cytoskeleton Organization Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Stress Fiber Assembly Positive Regulation Of Stress Fiber Assembly Actin Filament Network Formation Establishment Of Centrosome Localization	Sperm Axoneme Assembly Visual Perception Protein Localization Striatum Development Hippocampus Development Cerebral Cortex Development Adult Behavior Melanosome Transport Protein Localization To Organelle Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Negative Regulation Of Multicellular Organism Growth Golgi To Plasma Membrane Protein Transport Fat Cell Differentiation Photoreceptor Cell Maintenance Brain Morphogenesis Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Non-motile Cilium Assembly
Pathways			BBSome-mediated cargo-targeting to cilium
Drugs
Diseases
GWAS		Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		22 interacting genes: ACTA1 ACTG1 APC BBS1 BBS2 BBS4 BBS7 CR2 EXOSC8 GRB2 LNPEP NCOA6 NLGN3 PFN2 PPARG PRKG1 RAC1 RANBP2 RNF5 TRIM21 YWHAZ ZMYND8	25 interacting genes: APOC2 BHMT CES1 CETP CNOT1 EEF1A1 EPAS1 EXOC7 FHOD1 FNDC3B GOT2 HNRNPF HSCB HSF4 KCNK17 KRT18 LMO4 MAP2K5 MDFI NRF1 PAX2 PSME3 RBPMS SPTSSA WRNIP1
Entrez ID		29109	583
HPRD ID		06049	05855
Ensembl ID		ENSG00000135723	ENSG00000125124
Uniprot IDs		A0A068F7M9 Q9Y613	Q9BXC9
PDB IDs		3DAD 6XF1 6XF2
Enriched GO Terms of Interacting Partners?
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