UBE2T and RNF128

Number of citations of the paper that reports this interaction (PubMedID 19549727)
74

Data Source:
BioGRID (two hybrid)

		UBE2T	RNF128
Description		ubiquitin conjugating enzyme E2 T	ring finger protein 128
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Cytoplasm Late Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoskeleton Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination DNA Repair Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination	Negative Regulation Of Cytokine Production Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Protein Stability Protein Localization To Lysosome Positive Regulation Of Protein Catabolic Process In The Vacuole
Pathways		Fanconi Anemia Pathway Synthesis of active ubiquitin: roles of E1 and E2 enzymes	Ub-specific processing proteases Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Breast cancer ( 23535733) Celiac disease ( 23936387)	Alcoholic chronic pancreatitis ( 28754779) Creatinine levels ( 31015462) Estimated glomerular filtration rate ( 31015462)
Interacting Genes		23 interacting genes: AMFR ARIH2 BRCA1 CDK2 CHEK1 FANCD2 FANCL LNX2 MARCHF5 MGRN1 PCGF2 PRKCG PRKN RNF128 RNF144B RNF31 RNF4 ROCK1 RPS6KA1 TRIM27 UBA1 UBA6 ZNRF2	16 interacting genes: APPBP2 CD151 CD40LG CD81 CEP76 OTUB1 SNX17 TBK1 TP53 UBE2D1 UBE2E1 UBE2H UBE2I UBE2N UBE2T UBQLN2
Entrez ID		29089	79589
HPRD ID		13704	02340
Ensembl ID		ENSG00000077152	ENSG00000133135
Uniprot IDs		A0A024R9A9 Q9NPD8	Q8TEB7
PDB IDs		1YH2 4CCG 5NGZ 5OJJ 6R75	3ICU
Enriched GO Terms of Interacting Partners?
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