GRIA3 and GRIP2

Number of citations of the paper that reports this interaction (PubMedID 9768844)
101

Data Source:
HPRD (two hybrid)

		GRIA3	GRIP2
Description		glutamate ionotropic receptor AMPA type subunit 3	glutamate receptor interacting protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Endocytic Vesicle Membrane AMPA Glutamate Receptor Complex Dendritic Spine Postsynaptic Membrane	Cytosol Plasma Membrane Postsynaptic Density Dendrite Postsynaptic Membrane Glutamatergic Synapse
	Molecular Function	Amyloid-beta Binding AMPA Glutamate Receptor Activity Ligand-gated Ion Channel Activity Signaling Receptor Activity	Signaling Receptor Complex Adaptor Activity Glutamate Receptor Binding
	Biological Process	Glutamate Receptor Signaling Pathway Ion Transmembrane Transport Ionotropic Glutamate Receptor Signaling Pathway	Notch Signaling Pathway Artery Smooth Muscle Contraction Positive Regulation Of Blood Pressure Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse
Pathways		Activation of AMPA receptors Trafficking of AMPA receptors Trafficking of GluR2-containing AMPA receptors Unblocking of NMDA receptors, glutamate binding and activation Unblocking of NMDA receptors, glutamate binding and activation Synaptic adhesion-like molecules	Trafficking of GluR2-containing AMPA receptors
Drugs		Glutamic acid Butabarbital Ethanol Lithium cation Aniracetam Talampanel CX-717 Fluciclovine (18F) Lithium citrate Lithium succinate Lithium carbonate
Diseases
GWAS		Mortality in sepsis ( 27639821)	Cognitive performance ( 19734545) SjÃ¶gren's syndrome ( 28076899)
Interacting Genes		12 interacting genes: ADRB2 CREBBP GRIA2 GRIP1 GRIP2 GZMB LYN NSF PICK1 PPM1G SDCBP SQSTM1	6 interacting genes: CSPG4 FMR1 FXR1 GFI1B GRIA2 GRIA3
Entrez ID		2892	80852
HPRD ID		02378	18994
Ensembl ID		ENSG00000125675	ENSG00000144596
Uniprot IDs		P42263 Q17R51 Q5XKG2	Q9C0E4
PDB IDs			1V62 1X5R
Enriched GO Terms of Interacting Partners?
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