GPX7 and ERO1A

Number of citations of the paper that reports this interaction (PubMedID 21215271)
87

Data Source:
BioGRID (protein complementation assay)

		GPX7	ERO1A
Description		glutathione peroxidase 7	endoplasmic reticulum oxidoreductase 1 alpha
Image
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Dendrite Intracellular Membrane-bounded Organelle
	Molecular Function	Catalase Activity Peroxidase Activity Glutathione Peroxidase Activity Protein Binding	Protein Disulfide Isomerase Activity Protein Binding Protein-disulfide Reductase Activity Disulfide Oxidoreductase Activity Oxidoreductase Activity Thiol Oxidase Activity FAD Binding
	Biological Process	Cellular Response To Oxidative Stress Cellular Oxidant Detoxification	Protein Folding Cellular Protein Modification Process Response To Oxidative Stress Response To Temperature Stimulus Animal Organ Senescence Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Extracellular Matrix Organization Endoplasmic Reticulum Unfolded Protein Response Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis Brown Fat Cell Differentiation Chaperone Cofactor-dependent Protein Refolding Release Of Sequestered Calcium Ion Into Cytosol Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia
Pathways		Detoxification of Reactive Oxygen Species	Insulin processing Detoxification of Reactive Oxygen Species
Drugs		Glutathione Glutathione Glutathione disulfide
Diseases
GWAS		Blood protein levels ( 29875488) Joint mobility (Beighton score) ( 27182965)	Heel bone mineral density ( 30598549) Urine 6-bromotryptophan levels in chronic kidney disease ( 32572055)
Interacting Genes		13 interacting genes: ASPH CEP70 CPEB2 CPNE7 ERO1A GET3 NCALD NTAQ1 SGTA SGTB TCF25 UBQLN2 UBQLN4	15 interacting genes: APPBP2 DYNLT1 EBF1 ERP44 GPX7 GPX8 KLHDC2 LHX4 LINC01554 OGT P4HB PDIA3 PDILT PELI2 RHOU
Entrez ID		2882	30001
HPRD ID		13606	13278
Ensembl ID		ENSG00000116157	ENSG00000197930
Uniprot IDs		Q96SL4	Q96HE7
PDB IDs		2P31	3AHQ 3AHR
Enriched GO Terms of Interacting Partners?
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