GRK6 and RCVRN

Number of citations of the paper that reports this interaction (PubMedID 12507501)
8

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		GRK6	RCVRN
Description		G protein-coupled receptor kinase 6	recoverin
Image
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane	Photoreceptor Outer Segment Photoreceptor Inner Segment Membrane Dendrite Perikaryon
	Molecular Function	Protein Kinase Activity G Protein-coupled Receptor Kinase Activity Protein Binding ATP Binding Beta-adrenergic Receptor Kinase Activity	Calcium Ion Binding Calcium Sensitive Guanylate Cyclase Activator Activity
	Biological Process	Protein Phosphorylation G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Signal Transduction Wnt Signaling Pathway	Signal Transduction Visual Perception Phototransduction Positive Regulation Of Guanylate Cyclase Activity Regulation Of Calcium Ion Transport
Pathways		G alpha (s) signalling events	Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade
Drugs			Myristic acid
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Blood protein levels ( 28240269) Cardiac troponin-I levels ( 31014085) Chronic kidney disease ( 20383146) Extremely high intelligence ( 29520040) Glycine levels ( 30837465) Intelligence (MTAG) ( 29326435) Metabolite levels ( 22916037) Neutrophil percentage of white cells ( 32888494) Tinnitus ( 33742053) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		19 interacting genes: ADRB2 BDKRB2 CHRM3 EDNRA EDNRB FBXO7 FSHR GIT1 ITGA5 KCNIP3 LTB4R PRSS23 RCVRN RHO SLC9A3R1 SNCA SNCB SNCG TBXA2R	12 interacting genes: CAV1 GIT2 GRK1 GRK2 GRK5 GRK6 IL15RA PQBP1 SMAD3 TGFBR2 TOP1 TP53
Entrez ID		2870	5957
HPRD ID		02925	01558
Ensembl ID		ENSG00000198055	ENSG00000109047
Uniprot IDs		B3KPS5 P43250	P35243
PDB IDs		2ACX 3NYN 3NYO	2D8N
Enriched GO Terms of Interacting Partners?
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