SREK1IP1 and PPCDC

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		SREK1IP1	PPCDC
Description		SREK1 interacting protein 1	phosphopantothenoylcysteine decarboxylase
Image		No pdb structure
GO Annotations	Cellular Component		Cytosol Phosphopantothenoylcysteine Decarboxylase Complex
	Molecular Function	Nucleic Acid Binding Protein Binding Zinc Ion Binding	Phosphopantothenoylcysteine Decarboxylase Activity Protein Binding FMN Binding Identical Protein Binding
	Biological Process	MRNA Processing RNA Splicing	Coenzyme A Biosynthetic Process
Pathways			Coenzyme A biosynthesis
Drugs			Flavin mononucleotide Pantothenoylaminoethenethiol
Diseases
GWAS		General cognitive ability ( 29844566)	Adverse response to chemotherapy (amenorrhea) in breast cancer ( 31371054) Apolipoprotein A1 levels ( 32203549) Blood trace element (Zn levels) ( 23720494) Caffeine consumption ( 21490707) Coffee consumption (cups per day) ( 31837886) Heel bone mineral density ( 30598549) Lymphocyte counts ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean reticulocyte volume ( 32888494) Multisite chronic pain ( 33830993) Neutrophil count ( 32888494) Platelet count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systemic lupus erythematosus ( 26502338) White blood cell count ( 32888494)
Interacting Genes		28 interacting genes: AGPAT3 C4orf45 CCNL1 CT45A1 DDIT4L ELOA2 FGF10 GTF2H4 H2BC15 HPRT1 HSD17B14 LYAR MACROH2A1 NKAPD1 NKAPL NME1 PPCDC PRPF40A PRR13 RBM39 RNF151 RP9 RP9P RPL9 SDCBP SDCBP2 STAC3 THAP1	13 interacting genes: CENPT DBI DDIT4L FOXR1 NAA80 NTAQ1 PLEKHF2 PPIG PSMA1 SREK1IP1 TXN2 UBE2I ZNF232
Entrez ID		285672	60490
HPRD ID		08210	14377
Ensembl ID		ENSG00000153006	ENSG00000138621
Uniprot IDs		Q8N9Q2	H3BQB0 H3BRQ0 H3BSE3 H3BU63 Q96CD2
PDB IDs			1QZU
Enriched GO Terms of Interacting Partners?
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