EPHA6 and EFNA4

Number of citations of the paper that reports this interaction (PubMedID 10607706)
20

Data Source:
HPRD (in vivo, in vitro)

		EPHA6	EFNA4
Description		EPH receptor A6	ephrin A4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection Receptor Complex	Extracellular Region Plasma Membrane Anchored Component Of Membrane Intrinsic Component Of Plasma Membrane
	Molecular Function	Molecular_function Transmembrane Receptor Protein Tyrosine Kinase Activity Transmembrane-ephrin Receptor Activity ATP Binding	Transmembrane-ephrin Receptor Activity Protein Binding Ephrin Receptor Binding
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Axon Guidance Biological_process Peptidyl-tyrosine Phosphorylation Positive Regulation Of Kinase Activity Ephrin Receptor Signaling Pathway	Cell-cell Signaling Axon Guidance Ephrin Receptor Signaling Pathway
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHA-mediated growth cone collapse EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells EPH-ephrin mediated repulsion of cells	EPH-Ephrin signaling EPH-Ephrin signaling EPHA-mediated growth cone collapse EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells EPH-ephrin mediated repulsion of cells
Drugs		Fostamatinib
Diseases
GWAS		Blood trace element (Cu levels) ( 23720494) Blood trace element (Zn levels) ( 23720494) Longevity ( 26912274) Obesity-related traits ( 23251661) Systolic blood pressure ( 29208002) Weight ( 28552196) White matter hyperintensity volume ( 33293549)	Adventurousness ( 30643258) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Prostate cancer ( 23535732) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		2 interacting genes: EFNA1 EFNA4	11 interacting genes: EPHA2 EPHA3 EPHA4 EPHA5 EPHA6 EPHA7 EPHA8 ITGB1 MAP2K4 TMEM147 TRARG1
Entrez ID		285220	1945
HPRD ID		13275	03224
Ensembl ID		ENSG00000080224	ENSG00000243364
Uniprot IDs		A0A0B4J1T8 B3KS12 Q6UWM0 Q9UF33	P52798
PDB IDs
Enriched GO Terms of Interacting Partners?
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