CCDC141 and TSC22D2

Number of citations of the paper that reports this interaction (PubMedID 27337956)
22

Data Source:
BioGRID (two hybrid)

		CCDC141	TSC22D2
Description		coiled-coil domain containing 141	TSC22 domain family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Neuron Projection
	Molecular Function	Protein Binding
	Biological Process	Cerebral Cortex Radially Oriented Cell Migration Centrosome Localization	Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress
Pathways
Drugs
Diseases
GWAS		Blood pressure measurement (cold pressor test) ( 24165912) Diastolic blood pressure ( 28135244 27841878 30578418) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heart rate ( 30166351 23583979) Heart rate response to exercise ( 29769521) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Left ventricular ejection fraction ( 33495596) Left ventricular end-systolic volume ( 33495596) Left ventricular global circumferential strain ( 33495596) Left ventricular mass ( 33495596) Mucinous adenocarcinoma in colorectal cancer ( 29942513) Number of live births ( 30188897) Number of pregnancies ( 30188897) Objective response to lithium treatment ( 26503763) PR interval ( 32439900) Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale) ( 28525603) Psychosis proneness (revised physical anhedonia scale) ( 28525603) Pulse pressure ( 30578418) QRS duration ( 30012220) QT interval ( 24952745 29874175) Resting heart rate ( 29769521 27798624) Serum polyunsaturated fatty acid concentration x Mediterranean diet adherence interaction in metabolic syndrome ( 31991592) Sick sinus syndrome ( 33580673) Smoking cessation ( 30617275)	Adiponectin levels ( 22479202) Apolipoprotein A1 levels ( 32203549) Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive decline rate in late mild cognitive impairment ( 26252872) Cortical surface area (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Glaucoma ( 31959993) Glaucoma (primary open-angle) ( 33627673 29891935) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Intraocular pressure ( 29235454) Macular thickness ( 30535121) Mean platelet volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Moyamoya disease ( 29273593) PR interval ( 32439900) Pulse pressure ( 27841878) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 27841878) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149) Triglyceride levels ( 32203549 32154731) Type 2 diabetes ( 30054458 30297969) Waist circumference ( 26785701) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		4 interacting genes: DISC1 HOMER3 RRAD TSC22D2	42 interacting genes: ANAPC10 ANKRD36 ARID2 ATP1B1 CCDC141 CCDC144A CLIP1 DNAAF11 ENOPH1 EPCAM F8 FLNB GPBP1 ITGA2 KIAA0586 LOXHD1 LPL MED13 MPDZ MSH3 MTIF2 NGRN OSBPL1A PRMT3 PSMA7 PSMA8 RBL1 REV1 RNF2 SAP18 SCEL SEC31A SNX3 SPEF2 STK39 TMA7 TTN UFM1 WNK3 ZMYM2 ZNF143 ZNF251
Entrez ID		285025	9819
HPRD ID		08257	11101
Ensembl ID		ENSG00000163492	ENSG00000196428
Uniprot IDs		B8ZZB3 Q6ZP82	B4DN36 O75157
PDB IDs
Enriched GO Terms of Interacting Partners?
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