LYPD5 and IFITM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LYPD5	IFITM3
Description		LY6/PLAUR domain containing 5	interferon induced transmembrane protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Anchored Component Of Membrane	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Early Endosome Membrane Late Endosome Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Immune Response Response To Virus Negative Regulation Of Viral Transcription Response To Interferon-gamma Response To Interferon-alpha Response To Interferon-beta Negative Regulation Of Viral Genome Replication Negative Regulation Of Viral Entry Into Host Cell Defense Response To Virus Type I Interferon Signaling Pathway
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Breast cancer ( 29059683 23535729) Reading or mathematical ability ( 25003214)	Eosinophil counts ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252)
Interacting Genes		8 interacting genes: BET1 EHHADH ERG28 ERMP1 IFITM3 NINJ2 PLPPR2 TSPO	27 interacting genes: ABHD16A AQP6 CD53 ELOVL2 ERGIC3 FAM210B FFAR2 FKBP7 GLP1R GPR37 GPRC5D KIR2DL3 LYPD5 MS4A3 NEDD4 OPRM1 PLP1 PTAFR REEP4 RETREG3 SGPL1 SLC10A1 SLC10A2 SLC16A7 TMEM14B TMEM86B VKORC1
Entrez ID		284348	10410
HPRD ID		08084	05719
Ensembl ID		ENSG00000159871	ENSG00000142089
Uniprot IDs		Q6UWN5	Q01628
PDB IDs
Enriched GO Terms of Interacting Partners?
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