SLC13A5 and KLHL20

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC13A5	KLHL20
Description		solute carrier family 13 member 5	kelch like family member 20
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Integral Component Of Membrane	Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Actin Cytoskeleton PML Body Axon Dendrite Cul3-RING Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Organic Acid:sodium Symporter Activity Protein Binding Citrate Transmembrane Transporter Activity Succinate Transmembrane Transporter Activity Sodium:dicarboxylate Symporter Activity	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding Interferon-gamma Binding
	Biological Process	Sodium Ion Transport Oxaloacetate Transport Fumarate Transport Alpha-ketoglutarate Transport Succinate Transport Citrate Transport Tricarboxylic Acid Transmembrane Transport Cellular Response To Lithium Ion Succinate Transmembrane Transport Anion Transmembrane Transport	Golgi To Endosome Transport Cytoskeleton Organization Protein Transport Protein Ubiquitination Response To Interferon-alpha Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K33-linked Ubiquitination
Pathways		Sodium-coupled sulphate, di- and tri-carboxylate transporters	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252) Economic and political preferences (time) ( 22566634) LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Metabolite levels (small molecules and protein measures) ( 27005778)	Feeling miserable ( 29500382)
Interacting Genes		18 interacting genes: ADAMTSL4 CD79A CYSRT1 GJA8 GOLM1 KLHL20 KRTAP1-3 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP3-2 KRTAP5-2 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 MDFI	42 interacting genes: ACTA1 ARHGEF12 ATG9A BCL6 BEX1 BEX2 BRINP2 C1orf216 C20orf85 C21orf58 CEP126 CIDEC CLCNKA COL8A1 CORO7 CRK CRMP1 DUSP21 ECT2 ENKD1 EPAS1 ERG28 GBP2 HR IVNS1ABP KLHL38 LRIF1 LUC7L2 MTNR1A NEDD9 NTAQ1 PIN1 PML PRMT6 RANBP3 RECK SLC13A5 STK16 SUV39H1 TFAP2D TNPO2 USP20
Entrez ID		284111	27252
HPRD ID		10512	13918
Ensembl ID		ENSG00000141485	ENSG00000076321
Uniprot IDs		Q68D44 Q86YT5	Q9Y2M5
PDB IDs		7JSJ 7JSK	5YQ4 6GY5
Enriched GO Terms of Interacting Partners?
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