GSDMA and CISD3

		GSDMA	CISD3
Description		gasdermin A	CDGSH iron sulfur domain 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Mitochondrion
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-4-phosphate Binding	Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Apoptotic Process Defense Response To Bacterium Pyroptosis	Protein Maturation By [2Fe-2S] Cluster Transfer
Pathways
Drugs
Diseases
GWAS		Asthma ( 31959851 20860503 31619474 29785011) Asthma (childhood onset) ( 24241537) Asthma (time to onset) ( 27130862) Asthma and hay fever ( 24388013) Asthma or allergic disease (pleiotropy) ( 29785011) Bipolar disorder ( 31043756) Bronchial hyperresponsiveness in asthma ( 27439200) Crohn's disease ( 28067908) Hematological parameters ( 19820697) Inflammatory bowel disease ( 28067908 23128233) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lymphocyte percentage of white cells ( 32888494) Refractive error ( 32231278) Systemic sclerosis ( 28314753) Ulcerative colitis ( 28067908) White blood cell count ( 22037903 20139978 21738480)	Lung function (FEV1/FVC) ( 28166213)
Interacting Genes		4 interacting genes: APOC1 APOC2 APOC4 CISD3	8 interacting genes: C17orf78 GAS2L2 GSDMA HEATR9 LRRC37A11P PIGW SLFN12L STAC2
Entrez ID		284110	284106
HPRD ID		17081	19534
Ensembl ID		ENSG00000167914	ENSG00000277972
Uniprot IDs		Q96QA5	P0C7P0
PDB IDs			6AVJ
Enriched GO Terms of Interacting Partners?
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