GOT2 and ZDHHC6

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		GOT2	ZDHHC6
Description		glutamic-oxaloacetic transaminase 2	zinc finger DHHC-type palmitoyltransferase 6
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Plasma Membrane Cell Surface T-tubule Protein-containing Complex Perikaryon Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	RNA Binding L-aspartate:2-oxoglutarate Aminotransferase Activity Phospholipid Binding Kynurenine-oxoglutarate Transaminase Activity Amino Acid Binding Enzyme Binding Pyridoxal Phosphate Binding Carboxylic Acid Binding Identical Protein Binding	Protein Binding Palmitoyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Protein-cysteine S-palmitoyltransferase Activity Protein-cysteine S-stearoyltransferase Activity
	Biological Process	2-oxoglutarate Metabolic Process Oxaloacetate Metabolic Process Aspartate Metabolic Process Aspartate Biosynthetic Process Aspartate Catabolic Process Glutamate Metabolic Process Female Pregnancy Lactation Response To Muscle Activity Fatty Acid Transport 4-hydroxyproline Catabolic Process Glutamate Catabolic Process To Aspartate Glutamate Catabolic Process To 2-oxoglutarate Response To Insulin Response To Morphine Response To Ethanol L-kynurenine Metabolic Process	Protein Targeting To Membrane Positive Regulation Of Mitochondrial Fusion Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation Protein Acylation
Pathways		Degradation of cysteine and homocysteine Glyoxylate metabolism and glycine degradation Gluconeogenesis Aspartate and asparagine metabolism Glutamate and glutamine metabolism
Drugs		Pyridoxal phosphate Aspartic acid Glutamic acid Cysteine 4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate
Diseases
GWAS		Aortic root size ( 21223598) Aspartate aminotransferase levels ( 33547301 29403010 33339817) Automobile speeding propensity ( 30643258) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) High density lipoprotein cholesterol levels ( 33339817) Impulsivity (attentional) ( 30718321) Metabolite levels ( 23823483) QT interval ( 19305408) Serum metabolite levels ( 33031748) Triglyceride levels ( 32203549) Urinary metabolite levels in chronic kidney disease ( 31959995) Uterine fibroid number (single vs multiple) ( 30196971)	Basophil count ( 32888494) High chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183) Metabolite levels ( 23823483)
Interacting Genes		12 interacting genes: APCS BBS2 CCL21 CSNK2A2 GAPDH GLRX GLUD1 HSPA8 MDH2 PC THOC7 ZDHHC6	2 interacting genes: GOT2 KHDRBS1
Entrez ID		2806	64429
HPRD ID		00684	15721
Ensembl ID		ENSG00000125166	ENSG00000023041
Uniprot IDs		P00505	A0A0D9SEX5 Q9H6R6
PDB IDs		5AX8
Enriched GO Terms of Interacting Partners?
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