GLUD2 and TOM1L1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GLUD2	TOM1L1
Description		glutamate dehydrogenase 2	target of myb1 like 1 membrane trafficking protein
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Cytosol	Cytoplasm Lysosome Endosome Golgi Stack Cytosol Endosome Membrane Membrane Extracellular Exosome
	Molecular Function	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity Glutamate Dehydrogenase (NADP+) Activity GTP Binding ADP Binding Leucine Binding	Protein Binding SH3 Domain Binding Protein Kinase Binding Clathrin Binding Protein Kinase Activator Activity Phosphatidylinositol Binding Ubiquitin Binding
	Biological Process	Glutamate Metabolic Process Glutamate Biosynthetic Process Glutamate Catabolic Process	Signal Transduction Protein Transport Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Mitotic Nuclear Division Regulation Of DNA Biosynthetic Process
Pathways		Transcriptional activation of mitochondrial biogenesis Glutamate and glutamine metabolism
Drugs		Glutamic acid NADH
Diseases
GWAS		Fibrinogen levels in ischemic stroke ( 26718567)	Carotid intima media thickness x smoking interaction ( 32117412) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) Systolic blood pressure ( 34074324) Urinary albumin-to-creatinine ratio ( 32600054)
Interacting Genes		1 interacting genes: TOM1L1	29 interacting genes: AMFR CCDC47 CELF1 COPS7A CWF19L1 DNAJB13 FYN GLUD2 GRB2 GSN HGS HNRNPH1 MAP3K3 NDC80 NOMO1 PDPN PELP1 PHYH PIK3R1 PWP2 RAB18 TASOR TOLLIP TSG101 TUBA1B UBC UBXN4 VAV2 VCP
Entrez ID		2747	10040
HPRD ID		02143	05266
Ensembl ID		ENSG00000182890	ENSG00000141198
Uniprot IDs		A0A140VK14 P49448	O75674 Q8NI65
PDB IDs		6G2U	3RRU
Enriched GO Terms of Interacting Partners?
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