HTATSF1 and GTF2F2

Number of citations of the paper that reports this interaction (PubMedID 10454543)
21

Data Source:
HPRD (in vitro, in vivo)

		HTATSF1	GTF2F2
Description		HIV-1 Tat specific factor 1	general transcription factor IIF subunit 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U2-type Spliceosomal Complex U2 SnRNP	Nucleus Nucleoplasm Transcription Factor TFIIF Complex Microtubule Cytoskeleton Transcription Preinitiation Complex
	Molecular Function	RNA Binding	DNA Binding DNA Helicase Activity Protein Binding ATP Binding RNA Polymerase II General Transcription Initiation Factor Activity ATP Hydrolysis Activity
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II Viral Genome Replication Regulation Of DNA-templated Transcription, Elongation	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter DNA Duplex Unwinding
Pathways			Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex RNA Pol II CTD phosphorylation and interaction with CE during HIV infection HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation Viral Messenger RNA Synthesis RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes FGFR2 alternative splicing RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes mRNA Capping mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Elongation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Pol II CTD phosphorylation and interaction with CE Signaling by FGFR2 IIIa TM Estrogen-dependent gene expression
Drugs
Diseases
GWAS			Normal facial asymmetry (angle of surface orientation score) ( 30631343) Type 2 diabetes ( 25760438)
Interacting Genes		20 interacting genes: APBB1 CCNT1 CDK9 CLK1 CSNK2A1 ERCC6 FEZ1 GTF2F2 HDAC6 POLR2A SF3A2 SNRNP70 SNRPB2 SRPK2 SRSF4 SUPT4H1 SUPT5H THAP1 WBP4 ZNF512B	34 interacting genes: AHR AR ARNT ATF2 ATF4 CEBPG CREB1 DYNLT2B FHL2 FOS GTF2B GTF2E1 GTF2E2 GTF2F1 HMGA1 HTATSF1 JUN KLF5 MAPRE3 MSX2 MYC POLR2A POLR2E RBPMS RPL27A TAF5 TBP TCEA1 TRAM2 TSC22D1 TSPAN3 URI1 YEATS4 ZMYND19
Entrez ID		27336	2963
HPRD ID		02282	01804
Ensembl ID		ENSG00000102241	ENSG00000188342
Uniprot IDs		O43719	A0A024RDU9 P13984
PDB IDs		2DIT 6N3D 6N3E 6N3F 6NSX 6Y50 6Y53 6Y5Q	1BBY 1F3U 2BBY 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6O9L
Enriched GO Terms of Interacting Partners?
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