RBMX and APOBEC3C

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		RBMX	APOBEC3C
Description		RNA binding motif protein X-linked	apolipoprotein B mRNA editing enzyme catalytic subunit 3C
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GO Annotations	Cellular Component	Euchromatin Extracellular Space Nucleus Nucleoplasm Spliceosomal Complex Membrane Protein-containing Complex Supraspliceosomal Complex Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex	P-body Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Binding RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Identical Protein Binding	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Deoxycytidine Deaminase Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Osteoblast Differentiation Transcription By RNA Polymerase II Membrane Protein Ectodomain Proteolysis Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Protein Homooligomerization Cellular Response To Interleukin-1	Cytidine Deamination Negative Regulation Of Transposition Cytidine To Uridine Editing Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Defense Response To Virus DNA Cytosine Deamination DNA Demethylation
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA RHOBTB2 GTPase cycle RHOBTB1 GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle	mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS		Pediatric autoimmune diseases ( 26301688)	Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		48 interacting genes: APOBEC3C CCDC33 CIRBP CLK1 CLK3 CMTM6 CNNM3 CSNK2A1 FUS FXR2 HNRNPK IL7R ITSN2 JAK2 KHDRBS1 KHDRBS2 KHDRBS3 LINC01232 LNX1 MAGOHB MYPOP NABP1 NFE2L2 NYX OGT PCDHB14 PRPF31 PRR3 PSMF1 RAMAC RBM3 RBM7 RBMY1A1 RBMY1E RBMY1F RBMY1J ROBO3 SNRPA SOCS3 SORBS3 SREK1 SRPK2 SRSF3 SRSF9 STAT5A TRA2B XRN1 ZNF490	19 interacting genes: CHTOP FBXO7 HHEX HNRNPK PRR3 RBMX RBMY1A1 RBMY1F RBMY1J SHBG SRPK2 STK4 SUN2 TRAF3 TRIB3 ZNF250 ZNF408 ZNF48 ZNF581
Entrez ID		27316	27350
HPRD ID		02186	09671
Ensembl ID		ENSG00000147274	ENSG00000244509
Uniprot IDs		P38159	Q9NRW3
PDB IDs		2MB0 2MKS	3VM8 3VOW
Enriched GO Terms of Interacting Partners?
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